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Flashcards in Pharm 16 Deck (31)
2

Cholinomimetics that increase outflow, open trabecular meshwork, and cause ciliary muscle contraction

Pilocarpine, carbachol, physostigmine

3

Nonselective alpha agonists that increases outflow, probably via the uveoscleral veins

Epinephrine, dipivefrin

4

Selective alpha agonists that decreases aqueous secretion

Apraclonidine, brimonidine

5

This diuretic decreases aqueous secretion due to lack of HCO3- ion. Causes drowsiness and paresthesias, alkalinization of the urine may precipitate calcium salts, hypokalemia, acidosis

Acetazolamide

6

This agent cause increased aqueous outflow

Prostaglandin PGF2a

7

Block L-type calcium channel

Calcium channel blockers

8

CCB with predominate effect on arteriole dilation

Nifedipine

9

Beta-blockers should be used cautiously in

Asthma (bronchospastic effects), diabetes (block signs of hypoglycemia) and peripheral vascular disease

10

Non-selective Beta-blocker also used for migraine prophylaxis

Propranolol

11

Non-selective Alpha1blockers use to treat pheochromocytoma

Phenoxybenzamine

12

For rebound HTN from rapid clonidine withdrawal

Phentolamine

13

Presynaptic Alpha 2 agonist used in HTN

Clonidine, and methyldopa

14

SE of methyldopa

Positive Comb's test, depression

15

SE of clonidine

Rebound HTN, sedation, dry mouth

16

Ganglionic blockers formerly used in HTN

Trimethaphan, and hexamethonium

17

Direct vasodilator of arteriolar smooth muscle

Hydralazine

18

Arterial vasodilator that works by opening K+ channels

Minoxidil

19

SE of minoxidil

Hypertrichosis

20

IV Drug used Hypertensive Crisis

Nitroprusside

21

Nitroprusside vasodilates

Arteries and veins

22

Toxicity caused by nitroprusside and treatment

Cyanide toxicity treated with sodium thiosulfate

23

Carbonic anhydrase inhibitor

Acetazolamide

24

MOA of loop diuretics

inhibits Na+/K+/2Cl- cotransport

25

Aminoglycosides used with loop diuretics potentiate adverse effect

Ototoxicity

26

MOA of thiazide diuretics

Inhibit Na+/Cl- cotransport

27

Class of drugs that may cause cross-sensitivity with thiazide diuretics

Sulfonamides

28

Used for SIADH

Demeclocycline

29

SE of demeclocycline

Bone marrow and teeth discoloration for children under 8 years of age

30

Other side effects of Quinidine

Thrombocytopenic purpura, and CINCHONISM

31

Major drug interaction with Quinidine

Increases concentration of Digoxin

32

DOC for digoxin induced arrhythmias

Phenytoin