Pharm 14

Question 2

Treatment of withdrawal syndrome involves

Answer 2

Long-acting sedative-hypnotic or a gradual reduction of dose, clonidine or propranolol

Question 3

Withdrawal from this drug causes lethargy, irritability, and headache

Answer 3

Caffeine

Question 4

W/D from this drug causes anxiety and mental discomfort

Answer 4

Nicotine

Question 5

Chronic high dose abuse of nicotine leads to

Answer 5

Psychotic state, overdose causes agitation, restlessness, tachycardia, hyperthermia, hyperreflexia, and seizures

Question 6

Tolerance is marked and abstinence syndrome occurs

Answer 6

Amphetamines

Question 7

Amphetamine agents

Answer 7

Dextroamphetamines and methamphetamine

Question 8

These agents are congeners of Amphetamine

Answer 8

DOM, STP, MDA, and MDMA “ecstasy”

Question 9

Overdoses of this agent with powerful vasoconstrictive action may result in fatalities from arrhythmias, seizures, respiratory depression, or severe HTN (MI and stroke)

Answer 9

Cocaine “super-speed”

Question 10

Most dangerous of the currently popular hallucinogenic drugs, OD leads to nystagmus, marked hypertension, and seizures, presence of both horizontal and vertical nystagmus is pathognomonic

Answer 10

PCP

Question 11

Removal of PCP may be aided

Answer 11

Urinary acidification and activated charcoal or continual nasogastric suction

Question 12

Only direct acting agent that is very lipid soluble and used in glaucoma

Answer 12

Pilocarpine

Question 13

These agents are used to treat dry mouth in Sj_gren’s syndrome

Answer 13

Pilocarpine or Cevimeline

Question 14

Indirect-Acting ACh Agonist, alcohol, short DOA and used in diagnosis of myasthenia gravis

Answer 14

Edrophonium

Question 15

Carbamate with intermediate action postoperative and neurogenic ileus and urinary retention

Answer 15

Neostigmine

Question 16

Treatment of atropine overdose and glaucoma (because lipid soluable). Enters the CNS rapidly and has a stimulant effect, which may lead to convulsions

Answer 16

Physostigmine

Question 17

Treatment of myasthenia gravis

Answer 17

Pyridostigmine

Question 18

Antiglaucoma organophosphate

Answer 18

Echothiophate

Question 19

Associated with an increased incidence of cataracts in patients treated for glaucoma

Answer 19

Long acting cholinesterase inhibitors

Question 20

Scabicide organophosphate

Answer 20

Malathion

Question 21

The most important cause of acute deaths in cholinesterase inhibitor toxicity

Answer 21

Respiratory failure

Question 22

The most toxic organophosphate

Answer 22

Parathion

Question 23

Treatment of muscarinic symptoms in organophosphate overdose

Answer 23

Atropine

Question 24

This agent regenerates active cholinesterase and is a chemical antagonist used to treat organophosphate exposure

Answer 24

Pralidoxime

Question 25

Prototypical drug is atropine

Answer 25

Nonselective Muscarinic Antagonists

Question 26

Cystitis, postoperative bladder spasms, or incontinence

Answer 26

Oxybutynin, dicyclomine

Question 27

Toxicity of anticholinergics

Answer 27

Anti-DUMBBELSS

Question 28

Another pneumonic for anticholinergic toxicity

Answer 28

"dry as a bone, red as a beet, mad as a hatter, hot as a hare, blind as a bat"

Question 29

Atropine fever is the most dangerous effect and can be lethal in this population group

Answer 29

Infants

Question 30

Contraindications to use of atropine

Answer 30

Infants, closed angle glaucoma, prostatic hypertrophy

Question 31

Prototype ganglion blocker

Answer 31

Hexamethonium