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Flashcards in Pharm 18 Deck (33)
2

Beta 1 agonists used in acute CHF

Dobutamine and dopamine

3

Diuretics work in CHF by

Reducing preload

4

Beta blockers work in CHF by

Reducing progression of heart failure (never use in acute heart failure)

5

Agent used in CHF that is a selective alpha and nonselective beta blocker

Carvedilol

6

Agent used in acutely decompensated CHF resembling natriuretic peptide

Nesiritide (Natrecor)

7

Warfarin is contraindicated in

Pregnancy

8

Anticoagulant of choice in pregnancy

Heparin

9

Route of administration of warfarin

Oral

10

Routes of administration of heparin

IV and subQ

11

SE of both warfarin and heparin

Bleeding

12

SE of heparin

Heparin induced thrombocytopenia (HIT)

13

Alternative anticoagulant used if HIT develops

Lepirudin

14

Antidote to reverse actions of warfarin

Vitamin K or fresh frozen plasma

15

MOA of aspirin

Irreversibly blocking cyclooxygenase

16

Agent used to treat MI and to reduce incidence of subsequent MI

Aspirin

17

Antiplatelet drug reserved for patients allergic to aspirin

Ticlopidine

18

SE for ticlopidine

Neutropenia and agranulocytosis

19

Effective in preventing TIA's

Clopidogrel and ticlopidine

20

Prevents thrombosis in patients with artificial heart valve

Dipyridamole

21

Block glycoprotein IIb/IIIa involved in platelet cross-linking

Abciximab, tirofiban and eptifibatide

22

Thrombolytic that can cause allergic reaction

Streptokinase

23

Thrombolytic used for acute MI and ischemic (non hemorrhagic) CVA

Tissue plasmin activator

24

SE of tPA

Cerebral hemorrhage

25

Antidote for thrombolytics

Aminocaproic acid

26

Agent to treat hypochromic microcytic anemias

Ferrous sulfate

27

Chelating agent used in acute iron toxicity

Deferoxamine

28

Agent used for neurological deficits in megaloblastic anemia

Vitamin B12

29

Agent used neutropenia especially after chemotherapy

G-CSF (filgrastim) and GM-CSF (sargramostim)

30

Treatment of patients with prior episodes of thrombocytopenia after a cycle of cancer chemotherapy

Interleukin 11 (oprelvekin)

31

Decrease intestinal absorption of cholesterol

Bile acid-binding resins

32

Cholestyramine and colestipol are

Bile acid-binding resins

33

Major nutritional side effect of bile acid-binding resins

Impair absorption of fat soluble vitamin absorption (A,D,E,K)

34

MOA of lovastatin (STATIN)

inhibits HMG COA reductase