Pharm 18

Question 2

Beta 1 agonists used in acute CHF

Answer 2

Dobutamine and dopamine

Question 3

Diuretics work in CHF by

Answer 3

Reducing preload

Question 4

Beta blockers work in CHF by

Answer 4

Reducing progression of heart failure (never use in acute heart failure)

Question 5

Agent used in CHF that is a selective alpha and nonselective beta blocker

Answer 5

Carvedilol

Question 6

Agent used in acutely decompensated CHF resembling natriuretic peptide

Answer 6

Nesiritide (Natrecor)

Question 7

Warfarin is contraindicated in

Answer 7

Pregnancy

Question 8

Anticoagulant of choice in pregnancy

Answer 8

Heparin

Question 9

Route of administration of warfarin

Answer 9

Oral

Question 10

Routes of administration of heparin

Answer 10

IV and subQ

Question 11

SE of both warfarin and heparin

Answer 11

Bleeding

Question 12

SE of heparin

Answer 12

Heparin induced thrombocytopenia (HIT)

Question 13

Alternative anticoagulant used if HIT develops

Answer 13

Lepirudin

Question 14

Antidote to reverse actions of warfarin

Answer 14

Vitamin K or fresh frozen plasma

Question 15

MOA of aspirin

Answer 15

Irreversibly blocking cyclooxygenase

Question 16

Agent used to treat MI and to reduce incidence of subsequent MI

Answer 16

Aspirin

Question 17

Antiplatelet drug reserved for patients allergic to aspirin

Answer 17

Ticlopidine

Question 18

SE for ticlopidine

Answer 18

Neutropenia and agranulocytosis

Question 19

Effective in preventing TIA’s

Answer 19

Clopidogrel and ticlopidine

Question 20

Prevents thrombosis in patients with artificial heart valve

Answer 20

Dipyridamole

Question 21

Block glycoprotein IIb/IIIa involved in platelet cross-linking

Answer 21

Abciximab, tirofiban and eptifibatide

Question 22

Thrombolytic that can cause allergic reaction

Answer 22

Streptokinase

Question 23

Thrombolytic used for acute MI and ischemic (non hemorrhagic) CVA

Answer 23

Tissue plasmin activator

Question 24

SE of tPA

Answer 24

Cerebral hemorrhage

Question 25

Antidote for thrombolytics

Answer 25

Aminocaproic acid

Question 26

Agent to treat hypochromic microcytic anemias

Answer 26

Ferrous sulfate

Question 27

Chelating agent used in acute iron toxicity

Answer 27

Deferoxamine

Question 28

Agent used for neurological deficits in megaloblastic anemia

Answer 28

Vitamin B12

Question 29

Agent used neutropenia especially after chemotherapy

Answer 29

G-CSF (filgrastim) and GM-CSF (sargramostim)

Question 30

Treatment of patients with prior episodes of thrombocytopenia after a cycle of cancer chemotherapy

Answer 30

Interleukin 11 (oprelvekin)

Question 31

Decrease intestinal absorption of cholesterol

Answer 31

Bile acid-binding resins

Question 32

Cholestyramine and colestipol are

Answer 32

Bile acid-binding resins

Question 33

Major nutritional side effect of bile acid-binding resins

Answer 33

Impair absorption of fat soluble vitamin absorption (A,D,E,K)

Question 34

MOA of lovastatin (STATIN)

Answer 34

inhibits HMG COA reductase