1.1.2 DT Anti Psychotic drugs (Bi) Flashcards Preview

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Flashcards in 1.1.2 DT Anti Psychotic drugs (Bi) Deck (30):
1

What is anti psychotic medication?

Medication used to treat serious mental illnesses such as schizophrenia

2

How many people have schizophrenia?

1 in 100

3

What are the positive symptoms of schizophrenia?

• hallucinations
• delusions
(The seeing/tasting/hearing things that aren't there)

4

What are the negative symptoms of schizophrenia?

Lack of something e.g a lack of emotion causing the individual to isolate themself

5

What is schizophrenia not?

Split personality

6

What are psychotic breaks?

Temporary breaks from reality experienced by those with schizophrenia

7

What are transitional anti psychotic drugs known as?

Neuroleptic drugs

8

How long have neuroleptic drugs been around?

Since the mid 1900s

9

How do neuroleptic drugs work in the treatment of schizophrenia?

reduce the activity of the neurotransmitter dopamine by blocking its post synaptic receptor sites, thus reducing the positive symptoms of schizophrenia

10

What is dopamine associated with?

High levels of dopamine are connected with the positive symptoms of schizophrenia

11

What are newer anti psychotic drugs known as?

Atypical anti psychotic drugs

12

Give an example of an atypical drug:

Clozapine

13

How do atypical antipsychotic drugs work?

They block receptors in the brain for several neurotransmitters, including serotonin. Clozapine temporarily blocks dopamine receptors, after which dopamine levels return to pre-drug levels

14

What occurs in a placebo trial?

Random allocation of individuals to the drug or placebo group

15

What is the best way to eliminate researcher bias?

A double blind trial, this also means fewer demand characteristics on the participants part

16

What does the placebo group act as?

It is the control group it acts as the baseline for comparison

17

How would you control EVs in a placebo trial using patients with schizophrenia?

You would use patients of the same age, who have been suffering with schizophrenia for a similar amount of time

18

What is a meta analysis?

Gathering and analysing existing data

19

How much do neuroleptic drugs reduce the positive symptoms of schizophrenia by?

75%

20

What percentage of patients are atypical drugs effective in reducing the positive and negative symptoms of schizophrenia?

50% of patients who don't respond to neuroleptic drugs

21

How many patients respond to neither neuroleptic or atypical drugs?

12.5% or one eighth

22

What are the advantages of antipsychotic drugs?

• patients no longer need to be institutionalised
• patients function better in society
• patients can engage in other forms of treatment

23

What side effects do neuroleptic drugs have?

• grogginess (50%)
• dry mouth (16%)
• blurred vision (16%)

24

What do 10-20% of patients treated with neuroleptic drugs develop?

Tardive dyskinesia - involuntary movements of the mouth and tongue

25

What is drug therapy otherwise known as?

Chemotherapy

26

What side effect can clozapine (atypical drugs) develop?

A fatal blood disease in 1-2% of patients, this requires weekly white blood cell monitoring and can cause weight gain

27

Why might schizophrenic patients not comply with treatment?

• don't think they need it
• feel better
• delusions - think it is poison
• side effects

28

What is revolving door syndrome?

Re-admission of patients after they discontinue their medication

29

What is the relapse rate of schizophrenic patients not taking their medication?

70% in the first year

30

Should patients be given antipsychotic medication without consent? E. G sectioned patients

Not in a fit state to decide themselves and if the doctor thinks it is best
But what about the side effects? Free will?

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