Flashcards in 3.3.5 Beta Blockers (modifying Stress) Deck (23):
What are beta blockers?
Drugs prescribed for heart conditions but can be used to treat physical symptoms of stress
(How they work) the body's response to stress involves activation of which NS?
(How they work) activation of the SNS leads to physical symptoms such as what?
Increased blood pressure
Increases heart rate
(How they work) symptoms can cause long term negative effects including what?
(How they work) what does it mean that beta blockers have antagonist action?
They reduce activity of the SNS and subsequent symptoms
(How they work) beta blockers block which receptors?
Block receptor sites for adrenaline and noradrenaline
(How they work) when adrenaline binds to receptor sites what does it do?
Causes muscle such as in the heart to increase in beating
(How they work) beta blockers slow what?
Breathing and heart rate
(How they work) beta blockers don't stop anxiety they instead do what?
Mask the outward signs of it
(Types) what are the two types of beta blockers?
(Types) what do non selective beta blockers do and give an example:
Block adrenaline and noradrenaline in other areas of the body
Block B1 and 2 receptors affecting the heart kidneys and liver
(Types) what do selective beta blockers do and give an example:
Affect mainly the heart blocking only B1 receptors
Little effect on rest of body
(Off label use) beta blockers are primarily prescribed for what?
Heart conditions and angina
(Off label use) beta blockers are prescribed off label for anxiety meaning what?
The manufacturer has not applied for a license for their use for anxiety
(Off label use) as they don't have a license they have not undergone what?
Clinical trials to test their safety and effectiveness for anxiety
(Off label use) when can a doctor prescribe beta blockers?
When the benefits outweigh the risks
(Musicians) what do musicians use beta blockers for?
To overcome stage fright and perform under pressure
(Musicians) Lockwood - of 2000 musicians how many used beta blockers? And how many uses them daily?
19% used them daily
(Sport) beta blockers have what effect?
Make the heart work more efficiently
(Sport) beta blockers have gained a reputation as what type of drug?
(Sport) since 2010 what has happened to beta blockers?
Banned by world antidoping agency for all Olympic sport
(Benzodiazepines) what do benzodiazepines do?
Increase effect of GABA making it hard for other neurotransmitters to stimulate the neurone
Calming effect on the brain