Chem ch 23 Flashcards
(120 cards)
1
Q
lipids - soluble in what?
A
naturally occurring, nonpolar, insoluble in water. soluble in organic solvent
2
Q
types of lipids (wtfgsse like lipids)
A
- fatty acids
- waxes
- triacylgylcerols aka triglcerides)
- gylcerophospholipids
- spingolipids
- sterols
- eicosanoids
3
Q
fatty acids - box the fat (how many carbon - fatty these years)
A
a long chain of carboxylic acids, straight chain, usually 12-20 carbons.
4
Q
2 types of fatty acids
A
saturated fatty acids (SFAs) or unsaturated fatty acids (one or more double bond - USFAs)
5
Q
waxes (waxes like ester, acid and alcohol)
A
It’s just an ester. acid + alcohol = ester and H2O, ie. long chain acid + long chain alcohol
6
Q
triacylgylcerols aka (triglcerides)
A
triester of glycerol (just 3 carbons with
O
||
CH3-O-C attached)
7
Q
gylcerophospholipids
A
has phosphate group on one carbon. Has a charged phosphate group. called diester lipid - also component of cell membrane
8
Q
spingolipids - polar or no polar? (spring in the pool)
A
these are polar - they have polar and nonpolar head
9
Q
types of spingolipids (2) (sping is smart sugar)
A
sphingomyelin
glycolipids
10
Q
sterols (CHB steroids)
A
4 rings. 1) cholesterol, 2) bile salts, 3) hormones
11
Q
eicosanoids (echo - 24/7)
A
signaling molecules. arachiodonic acid - 20 carbons with 4 double bonds
12
Q
fatty acids - saturated
A
no double or triple bond
13
Q
saturated fatty ACIDS - examples (saturated LMPS in laura)
A
lauric acid
myristic acid
palmitic acid
stearic acid
14
Q
2 types of unsaturated fatty acids - aka monounsaturated fatty acids
A
one double bond
15
Q
unsaturated fatty acids - 2 numbers mean…
A
carbon 1st and number of bonds 2nd
16
Q
essential unsaturated fatty acids (lin uncool)
A
linoleic acid and linolenic acid
17
Q
omega 3 (and how many carbons?) (the omega is down by 14-1)
A
14-1 (1 is the number of bonds, if you’re naming it this way), first double bond away from carboxylic group is on carbon 3. Can be named 14-1 fatty acid. IT could be 14-2 omega 3, also, just wherever the first double bond is.
18
Q
omega 6
A
first double bond away from carboxylic group is on carbon 6
19
Q
waxes (wax evenly, ester is waxy) - What is the Rule???
A
fatty acids ester. R has to be even number of carbon (waxes don’t have odd #s) R prime is 24-36 carbons. R is 16-36 carbons
20
Q
function of waxes
A
protecting coating on fruits, leaves, animal skin or fur and aquatic birds
21
Q
ester will have a..
A
COO in it
22
Q
triacylglycerols - 2 major classes (try animals or veggies)
A
animal fat or vegetable oil. They are triester (3) of glycerol.
23
Q
R, R prime, R double prime are…
A
vegetable oil, are unsaturated
24
Q
animal fat (saturate the animals)
A
mostly saturated fatty acids
25
function of triacyclglycerols (store the tricycle)
used as longterm storage of energy. can provide a thermal insulation, and protective padding.
26
reactions of fatty acids (think saturated and non)
hydrogenation and hydrolysis
27
partial hydrogenation is bad..
because it creates trans fat, it is harder to digest due to higher melting point
28
hydrolysis of triacyleglycerols (water splits it down the middle)
THIS IS IN ACIDIC SOLUTION. the result is glycerol + 3 fatty acids.
O
||
The CH2-O-C-R group is just split in half and you're left with a gylcerol and 3 fatty acids.
29
hydrolysis of triagylcerols in basic solution (basic tricycle makes basic soap)
soap - in basic solution it's called saponification
30
saponification (soap needs water - think 3 glycerol soap)
hydrolysis of triagclyglycerols in basic solution
31
phospholipids
(most important)
32
sphingomyelin (sphingosine)
nerve fiber and brain tissue
33
glycolipids
a phospholipids with a fatty acid bonded on carbon #2, NH2 and a sugar on C1 (OH) group on sphingosine. cell membrane
34
sterols (cb for steroids)
1. cholesterol
2. bile salt (essential for digestion of fats and oils
for emulsification of fats. formed in the liver, stored in gall bladder, released in small intestine)
35
cholesterol
be able to identify it
36
mineralocorticoids (to the mines)
involved with maintaining the salt balance in the body. simulates absorption of Na by kidneys.
37
hormones with sterol nucleus (think roid and you know the last one)
1. mineralocorticoids (ex. aldosterons)
2. glucocorticoids
3. sex hormones
38
glucocorticoids (it's in the name)
cortisone (anti-inflammation) involved in metabolism of carbohydrates/protein/fat. they have anti-inflammatory activity.
39
sex hormones
lipids
1. testosterone
2. androsterone
affect sexual development or reproduction
40
cell membrane structure
lipid bilayer composed of 2 parallel sheets of lipid molecules arranged tail to tail.
41
main components of cell membrane (PLLG the membrane) think protein
lipids, protein, gylcoprotein, lipoprotein
42
2 types of protein in cell membrane
1. peripheral protein
| 2. integral protein
43
3 types of transport
simple diffusion (passive), active transport, facilitated diffusion
44
simple diffusion
high to low concentration, CO2, O2, NO - use simple. small mostly non-polar.
45
active transport
low concentration to high concentration. This uses ATP
46
facilitated diffusion
ie - glucose. needs to go from high to low concentration using protein channels. no energy is needed.
47
how to tell if it's a reducing sugar or not
if it has a free C=O-O or a C-H=O
48
hemiacetals have an...
OH group, acetals just have 2 O groups
49
glycosidic bond/glycoside
the formation of acetals or just the bond linking disaccharides and monosaccharides
50
enzymes provide an..(show me another way enzyme)
alternate pathway lowering the activation energy
51
eicosanoids structure (eco cooed at the ring)
long chain w/ COOH at the end, but also the ring structure attached
52
sterol structure
4 fused rings
53
examples of unsaturated fatty acids (don't need to memorize)
oleic acid - olive oil - 18 carbons, one double bond.
| linoleic acid - 18-2 - vegetable oil. linolenic acid - 18-3 - canola oil. arachidonic acid - 20 -4 - liver animal fat.
54
monosaturated fatty acids - what do the number represent?
the first is the # of carbons, then 2nd is the # of double bonds.
55
the number of double bonds raises or lowers the melting point?
lowers
56
are fatty acids cis or trans?
only cis, no trans in nature
57
arachidonic acid (spider in liver 24.7)
20-4, liver, animal fat
58
linoleic and linolenic are essential or not?
essential, because our bodies can't make it
59
cis can be converted to...
trans fat
60
memorize the structure of..
triglycerol
61
triglycerides aka triglcyerols ex. (tricycle if veggies and animal)
```
vegetable oil, unsaturated.
animal fat (mostly saturated fatty acids)
```
62
which triglyceride/triglycerol is the ONLY unsaturated fatty acids? (Veggie is liquid)
vegetable oil
63
if you see NaOH as a base, it's....
basic
64
glycerol-3 phosphate
a glycerol w/ a phosphate group on the 3rd carbon
```
CH2- OH
|
CH - OH
|
O
||
CH - O - P - O
|
O
```
65
polar part of the phospholipid
the head, the PO4(-2) part
66
nonpolar part of the phospholipid (cat tail and water)
fatty acid tails
67
sphingosine
it's the backbone
68
sphingomyelin (type of sphingo)
brain tissue and main component of coating around nerve fibers (myelin sheath)
69
glycolipids (type of sphingo)
phospholipids, with an NH2 bonded on carbon #2, and a sugar on carbon #1. sphingosine backbone. have carbohydrate attached
70
sphingomyelin is a type of what?
phospholipid
71
glycolipid is important component of...(the main thing)
cell membrane
72
bile salt essential for...
digestion of fats and oils (in small intestine) their job is emulsification of fats. they are synthesized in the liver. stored in gall bladder. can be released in small intestine.
73
when you shake phospholipids in the water, they make
micelles - no polar part of molecule goes inside micelle and makes a ball
74
in cholesterol, one ring is...
unsaturated
75
cholesterol is polar or nonpolar?
slightly polar bc there is one OH group
76
bile acids are polar or nonpolar?
polar, more polar than cholesterol bc they have more OH groups
77
ex of mineralocorticoids (alden in the mine)
aldosterone
78
aldosterone
involved with the salt balance in the body. stimulates absorption of Na+ or K+ by kidneys
79
micelles are also called...(my lips)
liposomes
80
important components of cell membrane (GLLP the protein for the membrane)
lipids, proteins, glycoprotein, lipoprotein
81
each layer of cell membrane is called...
leaflet, polar part outside, nonpolar facing inward
82
2 types of protein in cells
1) peripheral - only on one face of bilayer - one leaflet
| 2) integral protein - makes channel extended through the cell membrane
83
step one structure
just remove the double bond and add CH2 for 2nd C, and an OH on the left side
84
peripheral protein
only on one side of bilayer (one leaflet)
85
integral protein
with channel extended through the cell membrane
86
lauric acid (laura loves 12 coconuts)
coconut oil - 12 carbons - source is coconut oil.
87
myristic acid (at 14, butter and nutmeg are mystical)
14 carbons, butter fat or nutmeg fat. Both have high melting and boiling points bc many carbons.
88
palmitic acid (palm reader at 16)
16 carbons, palm oil
89
stearic acid (cocoa sterile at 18)
18 carbons, all animal fat or cocoa butter.
90
triacylglycerols - characteristics (tricycles don't like water or membranes)
no charge, nonpolar, hydrophobic. can't be part of the cell membrane.
91
sphingomyelins - make up
contain a charged phosphate group
92
gylcolipids - make up
contain a sugar group
93
waxes structure
just an ester in the middle, and only C and Hs on either side
94
Triacylglycerols - structure
3 carboxylic acids
95
Glycerophospholipids function - (glossy phospho is boss)
help to control the flow of molecules into and out of cells
96
Sphingomyelins - structure
amides derived from an amino alcohol (sphingosine) - also have a phosphate group
97
if there is a C=O-O-H at the end, it's a...
fatty acid
98
Polyunsaturated fatty acids have...
more than one carbon–carbon double bond.
99
if there is an H2-O, it's an..
alcohol. No matter what else is attached to it
100
All fats and oils are..(try the fats and oils)
triglycerols (think 3)
101
what makes the melting point lower?
the more double bonds, the lower the melting point
102
saturated fat - appearance
straight chains
103
unsaturated fats - appearance
kink where the double bond is - they're bent
104
Triacylglycerols are polar or nonpolar? (tricycles cant swim)
Nonpolar and hydrophobic
105
The three major kinds of cell membrane lipids in animals are...(think lipids and crisco)
phospholipids, glycolipids, and cholesterol.
106
what has 2 tails instead of one? (phosphate likes 2)
phospholipids
107
Glycerophospholipids (split the name in 2 and that’s what it is)
Two of the ester bonds are with fatty acids, 3rd is phosphate. It's just 3 (triacylglcerol) with a phosphate as the last one
108
fatty acids are..(the numbers) (fatty at this age)
carboxylic acids with 12 - 22 CARBONS - this is important
109
all lipids are nonpolar except...(phosphate is the key to water)
sphingolipids and glycerophospholipids
110
higher the carbon, the higher the...
melting point
111
how to identify a wax (what number)
it will be an even # of carbons with an ester (COO) (24 - 36 carbons, including the COO one)
112
remember to count...
the carbons when you identify structures
113
memorize gylcerol structure
it's just 3 CH2 with OHs attached
114
triglyceride structure (also called triacylglycerol) (TRI to remember the carboxylic part)
just a gylcerol - the OH becomes O, with an ester attached at all 3. basically just a =O attached to all 3 glycerols.
115
fats and oils are...(fatty acids on tricycles)
triacylglycerols
116
full hydrogenation is...
fine, partial is the one that can cause trans fat
117
hydrogenation of fatty acids
if unsaturated - undergo hydrogenation (think of H added to alkene becomes alkane) of unsaturated fatty acid. partial hydrogenation may convert some of the cis configuration to trans
118
hydrolysis of fatty acids (tracylglycerols)
119
if there is an Na+ or NaOH it's...
soap
120
ester looks like (Oh Oh ester)
O
||
O - C - C
