Pharm study guide 2 Flashcards
(79 cards)
ACE inhibitors - adverse effects (Ace ventura makes me swell and cough)
Swelling of the tongue, lips, face and throat. dry, non productive cough that is reversible with discontinuation of the therapy
who is not suitable for ACE inhibitors? (Ace ventura doesn’t mix with potassium)
Patients with a baseline potassium level of 5mEq/L or higher may not be suitable candidates for ACE inhibitor therapy, because these drugs can promote hyperkalemia.
A first dose hypotensive effect can cause a significant decrease in blood pressure with (Ace is significant)
ACE Inhibitors
Other adverse effects of ACE Inhibitors include (Ace cupcakes make kalema hyper and puffy)
a loss of taste, hyperkalemia, angio edema and renal impairment.
ACE Inhibitors and ARB’s appear to be
equally effective for the treatment of hypertension. Both are well tolerated.
The advantage of ARB’s over ACE Inhibitors is (no cough from arby’s)
that it does not cause a dry cough.
Calcium Channel Blockers may be used to treat (Calcium channel blockers HAD worked)
angina, dysrhythmias, and hypertension
what determines the regulation of arterial blood pressure?
Cardiac output and systemic vascular resistance
Weight reduction and restricted salt intake can be tried first before
being placed on medications for borderline hypertensive patients
what to give in a hypertensive emergency? (Arby’s in an emergency)
Angiotensin receptor blockers (ARB’s) are potent vasodilators bc they decrease systemic vascular resistance (SVR) and decrease pulmonary vascular resistance (PVR).
ARB’s - what action? (it’s in the name)
ARB’s will block angiotensin II from binding to its receptors on the muscles surrounding blood vessels. As a result, blood vessels enlarge (dilate) and blood pressure is reduced.
According to current hypertension management guidelines, initial anti-hypertensive drug therapy for a newly diagnosed hypertensive patient would most likely include
Thiazide diuretics
Comprehensive therapy for high blood pressure very often is
life-long.
How often to check BP if you have HTN?
Blood pressure checked once a week and keep track of the readings is highly suggested.
adverse effect for older pts - prazosin (Minipres®)
prazosin (Minipres®) for hypertension. One adverse effect is of most concern for the older adult patient taking this class of drug is Orthostatic hypotension
A patient diagnosed with “elevated blood pressure” has a reading of
120-129 and less than 80
Digoxin-immune Fab (Digibind®) is a
antidote to digoxin toxicity.
Digoxin-immune Fab (Digibind®) MOA
will bind to circulating digoxin and facilitate therapeutic serum concentration.
Digoxin Therapeutic levels are (Selene absolutely cannot dig)
0.5 - 2.0 nanograms/ml.
early and late signs of dig toxicity
early stages with anorexia and late stage of visual changes.
what increase dig toxicity?
Low potassium or magnesium levels can increase digoxin toxicity
A patient has received an IV dose of adenosine (Adenocard) , and almost immediately (Aden is dead)
the heart monitor shows asystole which is to be expected. It is designed to do so to reset the rhythm.
adenosine adminstration (A den next to my heart)
The medication should be given as close to central circulation as possible
adenosine half-life?
It has an extremely short half-life
