Inf&Imm: ZSO 9 (deel 1) Flashcards

(7 cards)

1
Q

Hoe komen antigenen terecht in lymfoïde organen?

A
  • via de afferente lymfevaten
  • dendritische cellen kunnen ze brengen
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2
Q

B-cel als APC

A
  • Antigen bindt aan BCR.
  • Receptor-gemedieerde endocytose.
  • Antigenverwerking
  • Presentatie in associatie met MHC-klasse II.
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3
Q

Immunologische synaps tussen APC en Tcel

A
  • T-cel — APC
  • LFA-1 — ICAM-1
  • CD4/CD8 —- MHC-II/-I
  • CD28 — CD80
  • CD154 — CD40
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4
Q

Op welk MHC reageren CD4+ TH-cellen

A

II

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5
Q

functie ICAM-1 — LFA-1

A

Adhesie

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6
Q

functie CD40 - CD154

A

TH-cel stuurt signaal in B-cel om CD80 tot expressie te brengen en ook stimuleert het class switching, affiniteitsmaturatie enzo

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7
Q
A
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