Microbiology 4 - Respiratory tract infection Flashcards Preview

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Flashcards in Microbiology 4 - Respiratory tract infection Deck (43)
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1

What is the most likely causative organism in a young patient with a lower lobe pneumonia, raised WCC and CRP?

Strep pneumoniae

2

Recall the appearance of streptococcus in culture

Gram positive cocci in chains

3

Recall how streptococcus is identified in the lab

Demonstrates alpha haemolysis

4

What is the most common pathogen implicated in CAP?

Streptococcus

5

Is streptococcus gram pos or gram neg?

Gram pos

6

Recall the 2 pathogens that can cause typical CAP

S. pneumonia
H influenzae

7

Which investigation are indicated in suspected CAP?

FBC, U&E, CRP, LFT
Blood cultures, sputum MC&S

8

What severity score can be used to score CAP?

CURB-65
Confusion
Urea (>7)
RR (>30)
BP (<90 systolic)
>65 years
Score 2 or above = admit

9

What is bronchitis?

Inflammation of medium sized airways

10

How does bronchitis appear on CXR?

Normal

11

How do haemophilus influenzae appear under the microscope?

Gram neg cocco-bacilli

12

On what sort of agar should H influenzae be cultured?

Chocolate agar

13

What colour sputum is produced in Strep pneumoniae?

Rusty

14

Which type of atypical pneumonia is associated with hyponatraemia?

Legionella

15

What is the special culture required for legionella?

Buffered charcoal yeast

16

What extrapulmonary features are likely in atypical pneumonia?

Hepatitis
Hyponatraemia

17

Which type of pneumonia is associated with confusion, abdo pain and diarrhoea?

Legionella

18

Which type of pneumonia is spread by birds?

Chlamydia psittaci

19

What is an empyema?

A collection of pus in the pleural cavity, gram-positive, or cultured from the pleural fluid

20

What are the key features of TB pneumonia?

Ethnicity
Prolonged prodrome
Fevers
Weight loss
haemoptysis

21

Recall 2 stains that can identify TB

Auramine stain
ZN stain

22

How can upper and lower respiratory flora be differentiated?

Bronchial lavage

23

Which type of pneumonia is common in the immunosuppressed (eg people who have had TB, HIV)?

Pneumocystis jirovecii

24

Recall 4 symptoms of pneumocystis pneumonia

Dry cough
Weight loss
SOB
Malaise

25

Recall the typical CXR finding in pneumocystis pneumonia

Bat wing

26

What is the most likely cause of pneumonia when there are interstitial changes on CT, neutropaenia and a history of ABx treatment?

Aspergillus fumigatus
This is particularly associated with prolonged ABx use - if ABx hasn't worked it may have a fungal cause

27

Which type of LRTI is more common in people who have had a BM transplant?

CMV

28

Which pneumonia pathogens can be tested for in urine?

Legionella
S pneumoniae

29

Which type of atypical pneumonia are those who work around farm animals at increased relative risk of?

Coxiella burnetti

30

What colour does gram stain appear with gram pos/gram neg bacteria?

Gram pos: blue
Gram neg: pink

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