Flashcards in Microbiology 5 - CNS infections and meningitis Deck (22)
Which antibiotic should be used first line in meningitis?
Is listeria meningitis is suspected, what antibiotic therapy should be used?
Ceftriaxone plus amoxicillin
Which pathogen is most likely to be the cause in myelitis?
What is myelitis?
Inflammation of the spinal cord
Recall the 3 most likely causative organisms in acute meningitis, and the most susceptible demographic of patient to each
N. meningitidis = young
S. pneumoniae = elderly (so vaccine at 65 years)
H. influenzae = those who haven't had HiB vaccine
What is the most commonn cause of meningitis in neonates?
Group B strep
What is the most likely causative organism in chronic meningitis?
What is the most likely causative organism in aseptic meningitis?
Describe the rash produced by meningococcal meningitis
Non-blanching purpuric rash
What is the most likely viral cause of encephalitis in the UK and worldwide?
Recall 3 possible routes of infection that may cause a brain abscess
Direct expansion from
- otitis media
- paranasal sinusitis
What is the most common type of spinal vertebral infection?
Pyogenic vertebral osteomyelitis
What is the most common cause of pyogenic vertebral osteomyelitis?
Infective endocarditis - staph/ strep can be 'flicked off' the valve
What is the first investigation to do in suspected meningitis?
Recall the stains used in CSF analysis to look for a) bacteria b) TB and c) fungi
a) gram stain
b) auramine stain
c) India ink
If "alpha haemolytic diplococci" are found in CSF, what is the pathogen causing meningitis?
What is the normal range for CSF protein?
What is the appearance of CSF in purulent vs aseptic vs TB meningitis?
Aseptic/ TB: slightly turbid or clear
What type of cell is elevated in the CSF in purulent vs aseptic vs TB meningitis?
Aseptic/ TB: lymphocytes
In which type of meningitis will gram stain antigen tests be positive?
Which type of meningitis produces the most protein in CSF?