Microbiology 3 - Antimicrobial Agents 2 Flashcards Preview

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Flashcards in Microbiology 3 - Antimicrobial Agents 2 Deck (6)
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1

What mnemonic can be used to help decide which antibiotic to use?

CHAOS
Choice depends on the:
Host charcteristics
Antimicrobial susceptibilities of the
Organism itself, as well as the
Site of infection

2

What is the Minimum Inhibitory Concentration and Breakpoint of an antibiotic useful for?

Working out sensitivity
MIC > breakpoint = resistant
MIC < breakpoint = sensitive

3

What antibiotic should be given for gram pos cocci in clusters?

Flucloxacillin

4

What antibiotic should be given empirically for gram neg cocci?

Ceftriaxone (could be meningococcus)

5

What is the "eagle effect"?

Increasing the penicillin dose --> decreasing antibacterial activitity after a point

6

How does the choice of antibiotic to treat UTI differ between community and hospital?

Community: nitrofurantoin/ trimethoprim
Hospital: cephalexin/ augmentin

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