Flashcards in Immunology 8 - Case studies in immunology Deck (6)
What are the clinical features of anaphylaxis?
IS AWFUL HARD:
Itch (palms, soles, genitalia)
Stridor (due to laryngeal obstruction)
Angiodema (of lips and mucous membranes)
Wheeze (due to bronchoconstriction)
Loss of Consciousness
Once someone has had an anaphylactic reaction, how should the cause be identified?
IgE blood test (skin prick should not be used)
What is "serum sickness"?
Type III hypersensitivity reaction - similar to allergy, eg to penicillin
Around how long after exposure does serum sickness develop?
Recall some symptoms of serum sickness
IgG deposits in:
- Joints (causing arthralgia)
- Kidney (causing AKI)
- Skin (causing a vasculitic rash)