Immunology 8 - Case studies in immunology Flashcards Preview

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Flashcards in Immunology 8 - Case studies in immunology Deck (6)
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1

What are the clinical features of anaphylaxis?

IS AWFUL HARD:

Itch (palms, soles, genitalia)
Stridor (due to laryngeal obstruction)

Angiodema (of lips and mucous membranes)
Wheeze (due to bronchoconstriction)
Flushing
Urticaria
Loss of Consciousness

Hypotension
Arrhythmias
Rhinorrhoea
D&V

2

Once someone has had an anaphylactic reaction, how should the cause be identified?

IgE blood test (skin prick should not be used)

3

What is "serum sickness"?

Type III hypersensitivity reaction - similar to allergy, eg to penicillin

4

Around how long after exposure does serum sickness develop?

3 days

5

Recall some symptoms of serum sickness

IgG deposits in:
- Joints (causing arthralgia)
- Kidney (causing AKI)
- Skin (causing a vasculitic rash)

6

How should serum sickness be managed?

Remove allergen
Corticosteroids
Manage fluids

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