Microbiology 11 - Viral Hepatitis Flashcards Preview

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Flashcards in Microbiology 11 - Viral Hepatitis Deck (20)
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1

Recall 2 RFs for Hep A transmission

1. Drinking from dodgy water supply
2. MSM

2

What is the incubation period for hepatitis A?

2-6 weeks

3

Which immunoglobulin is indicative of current Hep A infection?

IgM

4

Which immunoglobulin is indicative of previous Hep A infection/ vaccine?

IgG

5

What test is used to identify acute hepatitis A?

Anti-hepatitis A virus IgM

6

For how long does hepatitis B infection have to persist to be considered "chronic"?

6 months

7

What is the incubation period for hepatitis B?

2-6 months

8

What are the complications of chronic hepatitis B?

Cirrhosis
Hepatocellular carcinoma

9

Recall the stages of hepatitis B infection

1. Immune tolerant
2. Immune reactive
3. Inactive HBV carrier state
4. HBe antigen negative chronic HBV
5. HBs antigen negative phase

10

What treatments are available for chronic hepatitis B?

Interferon alpha
Lamivudine
Tenofovir

11

What does the hepatitis B vaccine contain?

Surface antigen

12

What are the main routes of transmission of hepatitis C?

Blood products
MSM

13

What % of people who get infected with hepatitis C go on to have chronic hep C?

60-80%

14

What is the incubation period of hepatitis C?

2 - 6 weeks

15

What test is used to diagnose hep C infection?

HCV RNA

16

What treatments are available for hepatitis C?

Interferon alpha
NS5B inhibitors

17

Hepatitis D infection is always superimposed upon which type of infection?

Hepatitis B

18

Which type of hepatitis only ever takes an acute course?

Hepatitis E

19

What is one particularly risky food for hepatitis E infection?

Wild boar

20

What are the possible complications of hepatitis E infection?

Bell's palsy
Guillain Barre

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