Flashcards in Microbiology 6 - GI infections Deck (37)
In a febrile patient with a GI infection, what are the key differentials?
1. Inflammatory diarroea
2. If no diarrhoea - enteric fever (typhoid/ salmonella)
In an afebrile patient with a GI infection, what is the top differential?
Secretory diarrhoea due to toxins (eg cholera)
What is the incubation period of campylobacter?
What is the incubation period of bacilus cereus?
Why does staph aureus food poisoning produce such rapid symptoms?
Toxin is pre-formed
What are the key cytokines involved in Staph aureus food poisoning?
IL-7 and IL-2
Describe the symptoms of S aureus food poisoning
Waterey, non-bloody diarrhoea
Describe the different toxins produced by bacilus cereus
Heat-stable toxin causes emesis
Heat-labile toxin causes diarrhoea
Only the heat-labile toxin is destroyed upon heating
Describe the diarrhoea produced by bacilus cereus
In what type of food might clostridia botulinum be found?
What type of clostridia spp causes food poisoning?
In what sort of food is clostridia perfringens found?
Which organism causes pseudomembranous colitis?
Which diarrhoeal disease is associated with antibiotic use?
Pseudomembranous colitis caused by C. difficile
What type of symptoms does listeria monocytogenes poisoning cause?
Recall 2 sources of listeria poisoning
Refringerated foods (eg sandwiches)
Is listeria alpha or beta haemolytic?
What is the causative organism in 'traveller's diarrhoea'?
Enterobacteriacae (usually the toxogenic form, ETEC)
What organism causes haemolytic uraemic syndrome?
Recall one very important thing to avoid in the management of enterobacteriacae poisoning
Recall 3 worrying species of salmonella
What symptoms are caused by S typhi infection?
Constipation and fever
Splenomegaly and ROSE SPOTS
What are the 2 key forms of shigella that cause disease in humans?
S flexneri (associated with MSM)
What disease pattern does shigella infection cause?
How should shigella infection be managed?
If really necessary, go for ciprofloxacin
What is the typical stool appearance in Vibrio cholerae infection?
Which organism is most likely to cause cellulitis in a scuba diver?
On what sort of agar can vibrio spp be grown?
For how long can campylobacter symptoms last?
Up to 20 days