Microbiology 20 - Neonatal and Childhood infection Flashcards Preview

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Flashcards in Microbiology 20 - Neonatal and Childhood infection Deck (10)
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1

What infections are currently screened for in pregnancy in the UK?

Hep B
HIV
Syphilis

2

What does TORCH stand for?

Toxoplasmosis
Other (syphilis, HIV, Hep B/C)
Rubella
CMV
HSV

3

What effect can toxoplasmosis have on the neonate?

Deafness, low IQ and microcephaly

4

Recall the symptoms of congenital rubella syndrome

Cataracts
CV syndrome
Sensorineural deafness
Brain pathology
BLUEBERRY MUFFIN RASH

5

What is the cause of a 'blueberry muffin rash' and in which infection is it seen?

Extramedullary haematopoiesis
Congenital rubella syndrome

6

Recall the symptoms of congenital HSV infection

Nasty disseminated infection, causing:
- Meningoencephalitis
- Ulcers and skin problems
- High mortality

7

What are the 'big 3' neonatal infections?

Listeria
E coli
Group B strep

8

Which neonatal infection could be described as 'catalase negative, beta haemolytic'?

GBS

9

What is the most common cause of late-onset sepsis in neonates?

Coagulase negative staph

10

What is the first line treatment for late-onset neonatal sepsis?

Cefotaxime (this is brain-penetrative) and vancomycin (this is good for staph)

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