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Step 1 > Test 36- HRM > Flashcards

Test 36- HRM Flashcards

1
Q

MEN1

A

pituitary
parathyroid
PANCREAS
**if you have 2 out of 3 evaluate for the THIRD type

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2
Q

hypercalcemia tx w/ neck surgery

A

parathyroid adenoma

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3
Q

drug that EXACERBATES hypoglycemia nad masks adrenergic sxs

should NOT be used in pts w/ DM

A

non selective b blockers

*use B1 if necessary

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4
Q

a pt that has low BS but never experiences sxs of hypoglycemia may be on which med

A

beta blocker

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5
Q

DM
necrolytic migratory erythema
anemia
diabetes

Dermatitis
Diabetes
DVT
Depression

A

Glucagonoma

*detect elevated levels of serum glucagon

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6
Q

HTN
hypokalemia
Metabolic alkalosis (high HCO3)
low renin

A

primary hyperaldosteorne

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7
Q

produced by sertoli cells

phyiological inhibiotr of FSH

A

inhibin B

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8
Q

controls LH concentration

A

testosterone feedback

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9
Q

males who only have one testes, will have fewer sertoli cells and therefore, decreased inhibiin and INCReased…

A

FSH

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10
Q

end product of sorbitol metabolism in health individuals

A

Fructose!!

Glucose> 
aldolose reducatse>
sorbitol>
sorbitol DH>
FRUCTOSE
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11
Q

where is sorbital pathway most active

A

seminal vesicles

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12
Q

retina, renal papilla, schwann cells

A

LESS sorbitol DH activity, so sorbitol isn’t converted to fructose

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13
Q

induces glycolysis by inducing PFK-1 and inhibits gluconeogenesis by inhibiting 1,6 BP

A

fructose 2,6 BP

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14
Q

upper GI ulcer
abdominal pain
diarrhea

A

gastrinoma

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15
Q

should be monitored in pts receiving amiodarone

A

thyroid function tests

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16
Q

proptosis

A

exopthalmos

17
Q

tx for severe grave’s opthalmopathy

A

high dose glucocorticoids

decrease severity of inflammation and extraocular volume

18
Q

increasing prevalence and stable incidence can be attriubted to…

A

factors that prolong duration of disease

improved quality of care

19
Q

palpitation
hand tremor
fatigability
mood swings will all improve w/ the use of this medicaiton for graves except for exopthalmos

A

beta blocker

20
Q

antiandrogens

A

finasteride
flutamide
ketoconazole
spironolactone

21
Q

flutamide

A

non steroid anti androgen that competes w/ test and DHT for TESTOSTERONE RECEPTORS

22
Q

why is flutamide used to tx prostate cancer

A

blocks stimulatory effect of androgens on primary tumor and metastases and leads to reduction in size

**the ONLY receptor blocker

23
Q

decreases conversion of testosterone to DHT and used to tx BPH nad male patern baldness

A

finasteride

24
Q

maintain spermatogenesis
release inhibin
secrete MIF

A

sertoli cells

25
Q

repro hormone levels seen in anorexic femlaes

A

low LH, FSH, estradio and estrone

hypogonadotropic amenorrhea

26
Q

linke between hyperprolactinemia and osteoporosis

A 
hyperprolactinemia>
hypogonadism>
reduced estrogen in women>
low estrogen>
acceerated bone loss
27
Q

47XXY

A

kinefelter

28
Q 
tall stature
small firm testes
azoospermia
gynecomastia
mild intellectual disability
A

klinefelter

29
Q

competitively inhibits thyroid uptake of radioactive iodine isotopes and is often administered after nuclear accidents to protect thyroid and prevent thyroid from radiation induced thrroid carcinoma

A

potassium iodide

30
Q

effects of prolonged hypogonadism caused by hyper PRL

A

low estrogen>
accelerated bone loss> osteoporosis

vaginal dryness

31
Q

high blood glucose levels in maternal circulation affect on fetus

A

cross placenta and cause fetal hyperglycemia and islet hyperlasia>

once delivered> hypoglycemia

32
Q 
confusion 
sweating
tremors
heart palpitations
relieved by honey water
A

hypoglycemia

33
Q

impt cause of hypoglycemia in diabetics

A

exercise

increased glucose uptake by muscles + rapid subcut insulin absorption when injection occurs in limb that is exercised

34
Q

administration of cortisol allows NE to reach full vasoconstrictive potential

A

permissive

cortisol is nOT additive/permissive, b/c it ALONE does not have any effects on vascular reactivity

35
Q

MCC of death in pts w/ DM

A

cardiovascular disease

36
Q

infant w/ FTT, jaundice and hepatomegaly

manifests after intro of fructose into the diet

A

aldolase B def

Step 1 (69 decks)

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