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Flashcards in Test 53 Deck (53):
1

prior to fertilization secondary oocytes are arrested in...

Metaphase of Meiosis II

2

cause of froth/foamy urine

proteinuria

heavy proteinuria seen in nephrotic syndrome can cause interstitial edema d/t decraese in serum albumin and total protein concentrations lower hte hplasma oncotic P

3

branch of the maxillary artery that enters the skull at hte foramen spinosum

MMA

4

pterion

bone is thin in this region and the MMA courses w/in the skull deep to this point> epidural hematoma

5

why do epidural hematomas require prompt treatment

lead to transtentorial herniation and palsy of CNIII

6

hilar adenopahty
pulmonary disease
non caseating granulomas (diff from TB)

SArcoidosis

7

what statin combinatoin increases the risk of myopathy in pts being treated for hyperlipidemia

statin + fibrates

GEmofibrozil increases the concentration of most statins > increased risk for myopathy

8

used to tx insomnia in pts employed in mission-critical positions, short half life minimizes undesirable day time SE

Triazolam

9

lorazepam

intermediate

10

diazepam
flurazepam
chlordiazepoxide

long

11

forms most of the diaphragmatic surface of the heart

inferior wall of left ventricle

12

supplies the inferior wall of left ventricle

posterior descending artery (most ppl derived from RCA)

13

supplies anterior 2/3 of IV septum and anterior wall of left ventricle

LAD coronary artery

14

supplies lateral and posterior superior walls of left ventricle

left circumflex

15

gives rise to LAD and left circumflex

left main coronary artery

16

acute marginal branches

arise from the RCA to suply teh wall of the right ventricle

17

initiates acute inflammation of the GB 90% of the time

acute calculous cholecysistitis

18

has 5'-3' exonuclease activity and 5' to 3' polyermase and 3'-5' exonnuclease activites

DNA pol 1

*5'-3' used to remove the RNA primer and damaged DNA

19

tx for DKA

iv hydration
normal saline and insulin

20

primary FV of s. pneuonia

polysaccharide capsule that inhibits phagocytosis

21

fever
cough
consolidation on chest xray

pneumonia

22

gram + diplococci that have alpha hemolysis on blood agar (green colonies)
bile soluble
optochin sensitive

s. pneumonia

23

bacterial organism destroyed by placement in hypotonic solution

damage to peptidoglycan cell wall by antibiotic against cell wall synthesis

24

peripheral edema
significant progeinuria
IgG4 Abs to phospholipase a2 receptor in podocytes

idiopathic membranous nephropahty

25

abnormal T cell production of glomerular permeability factor> fusion of foot processes

minimal change disease

26

abnormal T cell production of glomerular permeability factor> fusion of foot processes

minimal change disease

27

Combined T and B cell dysfxn
severe bacterial and viral infections
candidiasis
persistent diarrhea
FTT

absent T cells and hypogammaglobulinemia

SCID


*thymic shadow not present d/t severe T cell def

28

chronic diarrhea
mucocutaneous candidiasis
severe bacterial and viral infections in infancy

absence of thymic shaddow

SCID


*thymic shadow not present d/t severe T cell def

29

ataxia
telangiectasias
sinupulmonary infections

ataxia telangiectasia

30

oculocutaneous albinism
pyogenic infections
neurologic dysfxn

Chediak higashi syndrome

31

severe bacteriala nd fungal infections
granuloma formation

chronic granulomatous disease

32

congenital heart disease
dysmorphic facies
hypocalcemia

DiGeorge

33

recurrent neisseria

C5-C9 def

34

recurrent infections that worsen w/ age
easy bleeding
eczema

WA syndrome

35

anti-inflammatory agent that DOES NOT impair platelet fxn

selective COX 2 inhibitors

36

nitrates>
reflex tachycardia by causing a relative hypotension that hte body responds to w/ catecholamine release.

how do you prevent this?

administer nitrates w a beta blocker

37

Etanercept

TNFa inhibitor added to MTX to tx moderate-severe RA

38

fusuion protein linking solubule TNFa receptor to Fc component of IgG1

reduces biological activity of TNFa by acting as a decoy receptor

ETANERCEPT

39

mab

monoclonal ab

40

cept

receptor molecule

41

nib

kinase inhibitor

42

nib

kinase inhibitor

43

exons of a gene are reconnected in multiple ways during post transcriptional processing> different mRNA sequences> different protein isoforms

alternative splicing

44

left untreated, where do gastric carcinomas metastasize to?

Virchow's node (left supraclavicular sentinel node)

Sister mary joseph nodule (subcutaneous mass in periumbilical region)

45

metastatic spread of adenocarcinoma to one or both ovaries

primary cancers of
stomach
breast
pancreas
gallbladder

46

enzyme w/ a molecular weight of 72kD

COX 2

47

Irreversibly modifies COX1/2

NSAIDS/aspirin

48

infliximab

irreversibly binds to and ]inhibits TNFa

49

chronic pathologic changes in spleens of pts w/ sickle cell anemia

repetitive splenic infarctions caused by splenic microvessel occlusion>
fibrosis, brownish discoloration>
need for autosplenectomy

50

reliable test

gives similar results on repeat measurements

51

validity (accuracy)

tests ability to measure what it's supposed to

52

foul smelling bulky floating greasy stool

malabsorption

53

dx of malabsorption

collect stool