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Flashcards in Test 48 Deck (64):
1

Commonly develops following aspiration in ALCOHOLICS

filamentous
branching
gram + bacteria and sulfur granules

Pulmonary actinomycosis

2

Commonly develops following aspiration in ALCOHOLICS

filamentous
branching
gram + bacteria and sulfur granules

Pulmonary actinomycosis

3

SE of statins

myopathy and liver toxicity (hepatitis) in some pts

4

endocardial cushion defects

DS

ASD
regurgitant AV valves

5

tetraology of fallot
aortic arch abnormalities

DiGeorge syndrome

6

hypertrophic cardiomyoaphty

Friedrichs ataxia

7

spinocerebellar degeneration w/ predominant spinal ataxia

Friedrichs ataxia

8

cystic medial necrosis of the aorta

Marfans

9

valvular obstruction d/t cardiac rhabdomyomas

tuberous sclerosis

10

coarctation of hte aorta

turners syndrome

11

coarctation of hte aorta

turners syndrome

12

IgM Ab specific for Fc component of self IgG

Rheumatoid factor

13

Bilateral pain
stifness
deformity of PIP and MIP
rheumatoid nodules

RA

14

Rheumatoid Factor

CD4T cells induce B cells to synthesize RF which is an IgM Ab for SELF IgG. It binds IgG and forms ICs in the serum. Deposition in the synovium/cartilage> activates complement in those locations> chronic inflammation

15

Rheumatoid Factor

CD4T cells induce B cells to synthesize RF which is an IgM Ab for SELF IgG. It binds IgG and forms ICs in the serum. Deposition in the synovium/cartilage> activates complement in those locations> chronic inflammation

16

Antimitochondrial Abs

PBC

17

ANA

many CT disorders

18

Anti-centromere

CREST

19

serums ability to agglutinate sheep RBC

Monospot test

20

Anti-phospholipid Abs

SLE
antiphopholipid Ab syndrome

21

hypercoagulatbility
paradoxical PTT
recurrent miscarriages

Antiphospholipid ab syndrome

22

Ab to DSDNA

SLE

23

How do you avoid drug TOLERANCE while taking nitrates.

Take in AM and afternoon than have nitrate FREE period every day

24

Pneumocystis jiroveci in a homeless pt

you should immediately think HIV since PJ exclusively affects immunocompromised people

25

characteristic sx of esophagitis

painful swalllowing

26

three main causes of HIV associated esophagitis

Candida
CMV
Herpes

27

Gray/white pseudomembranes

yeast cells and pseudohyphate that invade mucosa cells

candida

28

small vesicles that evolve into PUNCHED out ulcers

intranuclear inclusions in multinuclear sq cells at margins of ulcers

HSV-1

29

linear ulceration

CMV

30

profuse watery diarrhea in HIV pts

Isopora belli

31

cardiomyopathy
achalasia
megacolon
megaureter

chronic CHAGAS cause dby trypanosoma cruzi

32

cardiomyopathy
achalasia
megacolon
megaureter

chronic CHAGAS cause dby trypanosoma cruzi

33

Used for short period to acheive rapid sx relief until slower acting drugs can take effect in pts w/ acute pain

prednisone

34

preferred tx for pts w/ moderate to severe RA

MTX

35

hypoxia induced vasoconstirction

COPD

36

how does chronic HTN lead to PH?

increased diastolic filling pressures to maintain SV/CO>
increase in LA pressure>
pulmonary venous congestion>
increase in pulmonary A pressure>
vasoconstriction

37

Aldosterone

absorption of Na

low of K and H ions

38

hemiparesis w/ the ARM affected more than the LEG

MCA occlusion

If in dominant hemisphere, aphasia may also occur

39

occlusion of left ACA

right hemiplegia with LE affected more than UE

40

occlusion of AICA

lateral inferior pontine syndrome

41

occlusion of PICA

lateral medullary syndrome

42

HOw does infection w/ M. pneumoniae lead to anemia?

shares Ags w/ human RBC>
when body mounts response against htsoe Ags it lyses RBC >
anemia

43

AR disorder in which lack of homogentisic oxidase BLOCKS metabolism of phenylalanine to tyrosine>
accumulation of homogentisic acid>
excreted as BLACK URINE

Alkaptonuria

44

Why is PO2 in the LA/Ventricle LOWER than that in the pulmonary capillaries?

mixing of oxygenated blood from the pulmonary veins w/ deoxygenated blodo from bronchial arteries and thesbian veins

45

AD disorder that results in GOF mutation in FGFR3 gene

achondroplasia

46

what is the chance of passing on achdondroplasia?

most individuals are HETEROZYGOUS> 50% chance of transmitting mutaiton to offspring

47

myxomatous changes in the media of large arteries are associated w/ what pathology?

cystic MEDIAL degeneration> aortic dissectionsa nd aortic aneurysms

48

Medial degeneration is associated w/ what syndrome?

Marfans

49

Tx for rat poisoning

fresh frozen plasma and vit K

50

What is in rat poisoning?

brodifacoum--> long acting 4-hydroxycoumarin derivative> coagulopathy and abnormal bleeding

51

heparin overdose

protamine sulfate

52

used immediately after ingestion of rat poison

syrup of ipecac

53

commonly used tx for Psoriasis

topical vit D analgos:
calcipotriene
calcitrol
tacalcitol

54

Meds that BIND vit D receptor and inhibit keratinocyte proliferation and stimulate keratinocyte differentiation

vit D analogs

55

gradually progressive dyspnea
bilateral reticulonodular opacities
restrictive pattern
pathcy interstitial lymphocytic inflammation and fibrosis of alveolar walls

pulmonary fibrosis

"honecomb"

56

drug commonly used to tx RA that can cause interstitial pneumonitis and fibrosis

MTX

57

>3 mos use of appetitie suppressants can lead to...

PH

fenfluramine
phenterine

58

dyspnea on exertion
RV hypertrophy> sudden cardiac death

PH

59

how do you distinguish different serotypes of s. pneumoniae?

capsular polysaccharide

60

pneumococcal polysaccharide vaccine

unconjugated vaccine that induces a T cell independent response

61

pneumococcal conjugate avaccine

contains polysaccharide material attached to protein Ag> more robust T cell dep response

62

caudal regression syndrome

agenesis of sacrum
flaccid paralysis of legs
dorsiflexed feet
urinary incontinence

63

what cuases caudal regression syndrome?

poorly controlled maternal diabetes

64

hwat pulls tropomyosin away exposing myosin binding sites

Troponin Ca complex