Test 27 Flashcards

(68 cards)

1
Q

location of compound tubular glands that secrete alkaline mucus

A

Brunner’s glands in the duodenum that secrete into ducts that empty into the crypts of Lieberkuhn

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

lymphoid aggregates specific to the ileum

A

Peyers patches

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

L/S ratio greater than 2 indicate

A

adequate surfactant produciton to avoid neonatal hyaline membrane disease

Lecithin production increases after 30,36 weeks, while syphingomyelin levels remain constant during the third trimester

Dipalmitoyl phosphatitoly choline and phosphatidly glycerol are major components of surfactant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

recall bias

A

inaccurate recall of past exposure by people in the study–ppl who have stuffered an adverse eent are more liekly to recal RFs than those w/out adverse experiences

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Referral bia

A

case and control pops differ d/t to admission/referral practices

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

detection bias

A

RF itself may lead to extensive diagnostic investigation and increase probability that disease is identified

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Lead time bias

A

screening test dx a disease earlier than it would have appeared by natural hx so that hte time from dx until death is prolonged

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

allocation bias

A

way tx and control groups are assembeled

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

sampling bias

A

non random sampling of a population–study populatoin has characteristics that differ from the target population

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

hereditary defect in renal PCT and intestinal AA transporter that prevents resorption of cystine, ornithine, lysine, arginine (COLA) across the intestinal and renal tubular epithleium

A

cystinuria (AR)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what complication is a pt w/ cystinuria at risk for developing

A

excess cystine in the urine can lead to recurrent precipitation of hexagonal cystine STONES> recurrent nephrolithiasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

tx for cystinuria

A
urinary alkalinization (K citrate, acetazolamide)
chelating agents
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

octahedron stones

A

calcium oxalate
calcium phosphate

sCuare

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

rectangular prisms (coffin lids) stones

A

Magnesium ammonium phosphate (struvite or triple phosphate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Yellow/red-brown diamond or rhombus

A

uric acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

effect of MI on CO

A

sharp DECREASE in CO ouput d/ tloss of myocardium (decreases slope and max height of line)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

effect of chronic anemia on CO

A

increases CO to meet metabolic demand of tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

effect of anaphylaxis on VR and CO

A

VR- decreases, d/t widespread venous and arteriolar dilation and increased capillary permeability

CO- increases/ d/t increased cardiac contractility to maintain bp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

flu like sxs and erythema chronicum migrans following hiking in new hampshire

A

early lyme disease

key LYME pie to the

Flu like sxs/Facial nerve palsy
Arthritis
Cardiac block
Erythema chronicum migrans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

AV block and bells palsy after hiking 6 mos ago

A

second stage of lyme’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

chronic assymmetric large joint arthritis and ecephalopathy following hiking months to years ago and bells palsy

A

lymes disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

how do you tx lymes

A

doxycycline

penicillin type antibiotics (ceftriaxone)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

lymes transmission

A

borrelia burgdorferia spirochete by bite of ixodes tick in NE of USa nd europe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

antimalarial drug used in prevention and tx of p. falciparum

A

mefloquine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
transplant pt w/ pneumonia and intranuclear and cytoplasmic inclusion bodies (OWLS EYES)
opportunistic infection w/ CMV
26
enveloped DS DNA virus
CMV- common in pts w/ lung transplants, can be treated prophylactically w/ valganciclovir
27
site of ribosomal RNA synthesis
nucleolus
28
APP, presenilin 1, presenilin 2
EArly onset alzheimers | APP is located on chrom 21 and is why pts w/ Downs get Alz
29
Apo E4
late onset Alz
30
ApoE2
decreased risk of Alz
31
Familial hyperhcolesterolemia
defect in LDL
32
mutation in b myosin heavy chain
hypertrophic cardiomyopathy
33
cardiac SE of doxorubicin (daunorubicin, epirubicin, BICINS)
form FREE radicals in the myocardium> dose related dilated CARDIOMYOPATHY> SXS of L and R ventricular CHF
34
9yo red colored urine, periorbital edema, mild pedal edema atopic dermatitis> predisposure to secondary skin infections impetigo
Antecedent skin infection + acute hematuria and edema> PSGN
35
MC cause of acute nephritis in children
PSGN
36
Abs form against Ag expressed by GAS during infection. Ab combine w/ AG to form ICs (type III) that are deposited along BM
PSGN | GAS- impetigo, cellulitis, pharyngitis
37
second MC cause of CAH
11B hydroxylase def prevents adrenal gland from synthesizing cortisol and aldosterone efficiently laeding to increased production of adrenal androgens d/t aldosterone and cortisol precursors being shifted there. Low cortisol further stimualtes production of ACTH> further increase in adrenal androgens
38
Female born w/ ambiguous genitalia, HTN and HYPOkalemia early in life.
11 hydroxylase def
39
MC type of CAH
21 hydroxylase def
40
Female w/ ambiguous genitalia (androgen excess) and HYPOTN and HYPOkalemia (mineralcorticoid def)
21 hydroxylase def
41
Females are born with NORMAL genitalia but males are undervirillized. AFfected individuals DONT undergo puberty and develop HTN and hypokalemia (excess mineralcorticoids)
17a hydroxylase
42
contralateral spastic rigidity hyperreflexia paresis (weakness in voluntary movement
UMN lesion (can affect any part of pyramidal motor system)
43
caudate nucleus
Huntingtons | lesions> chorea and athetosis (slow writhing of fingrs/movements)
44
Integrates body state and emotions with ANS and conscious experience of vsiceral sensations
insular cortex
45
initiates movements | lesions> contralateral tremor, bradykinesia, rigidity
putamen
46
pure motor weakness affecting contralateral arm, leg and lower face *contralateral spasticity, hyperrefelxia, positive Babinski
Internal capsule stroke
47
MAO inhibitor that can prevent MPTP induced damage of dopaminergic neurons
selegiline (delays parkinsons!)
48
Preferred combination for treating Parkinsons
Selegiline Anticholinergics Amantadine then levo/carbi introduced
49
Amantadine
antiviral influenza agent has some dopaminergic and anticholinergic actions> can provide mod improvement to Parkinson pt
50
Increases levels of DA in the brain
Ldopa
51
carbidopa
given with L dopa to increase bioavailability in the brain
52
Peroglide
DA agonist, providesmodest improvement in park sxs
53
High fever cough confusion diarrhea
Legionella pneumophilia
54
MC lab abnormality seen w/ legionella
HYPOnatreamia sputum shows many neutrophils
55
this disease can be suspected w/ recent exposure to contaminated water (cruise ships, spas,, hotels)
Legionella
56
cold agglutinin formation
mycoplasma pneumonia (young adults)
57
Healthy volunteers orally inoculated w/ pathogenic strains of c. diff don't develop signs of infection. Which protective mechanism is responsibel?
Intestinal bacteia that are normally present in our flora effectively suppress overgrwoth of d. diff and compete for nutrients and adhesion to the gut
58
class of drugs taht has been showsn to decrease the progression of diabetic nephropathy
ACE-I and ARB
59
first line medication for tx of essential HTN
HTZ
60
Hormones that use G proteins and cyclic AMP
Glucagon PTH TSH (FLAT ChAMP + calcitonin, GHRH, glucagon)
61
Activate PPAR-gamma and alters trxn of genes responsible for glucose and lipid metabolism
TDZ--> decrease insulin resistance
62
Activate PPAR-gamma and alters trxn of genes responsible for glucose and lipid metabolism
TDZ--> decrease insulin resistance
63
what reduces the risk of non-hereditary ovarian and endometrial cancer
OCPs!! multiparity breast feeding
64
what is the most potent cerebral vasodilator
pCO2 decreases vascular resistance leading to increased cerebral perfusion and ICP
65
affect of COPD on pulmonary resistance
chronic hypoxia caused by COPD> pulmonary vasoconstriction
66
MC malignant hepatic lesion
metastis form anotehr primary site (breast, lung, colon)
67
MC malignant hepatic lesion
metastis form anotehr primary site (breast, lung, colon)
68
Urinary urgency, frequency, hesitency assocaited w/ BACK PAIN in an ELDERLY man
metastatic prostate cancer **strong predilection for BONES