Test 58

Question 1

tx for herpes

Answer 1

Nucleoside analogs (acyclovir)

incorporated into newly replicated viral DNA and terminate viral DNA synthesis

Question 2

prevent viral attachment to target cells

Answer 2

enfuvirtide

Question 3

inhibits viral protease

Answer 3

indinavir (HIV)

Question 4

prevents virion release form infected cells

Answer 4

neuramindase inhibitors

Question 5

upregulates IFN syntehsis in infected cells

Answer 5

interleukins

Question 6

schizoaffective disorder

Answer 6

psychosis must occur in ABSENCE of major mood epid

Question 7

psychotic features occur EXCLUSIVELY During mood episodes

Answer 7

major depressive

bipolar disorder

Question 8

RBCs w/ multiple smaller round nucleated cells

Answer 8

plasmodia (malira) infection

Question 9

tx for RBC forms of malaria

Answer 9

chloroquine

mefloquine

Question 10

tx required to kill vivax and ovale liver shizonts

Answer 10

primaquine

Question 11

prohylaxis and tx of p. jiroveci

Answer 11

pentamidine

Question 12

antiparasitic drug used to tx chagas

Answer 12

nifurtimox

Question 13

tx for onchocerciasis

Answer 13

ivermectin

Question 14

influenced by disease prevalance

Answer 14

PPV and NPV

Question 15

earliest manifestation of diabetic nephropathy

Answer 15

moderately increased albuminuira (

Question 16

99mmTc pertechnetate scan accumulation and lower GI bleeding

Answer 16

meckels diverticulum

99Tc identifies ectopic gastric epithelium and helps to make dx

Question 17

initiates an aortic dissection

Answer 17

hemodynamic stress> tearing of aortic INTIMA w/ blood dissecitng through MEDIA>
itnramural hematoma that can extend proximally and distally

Question 18

intimal fatty streak

Answer 18

initial lesion of atherosclerosis

Question 19

medial calcific sclerosis

Answer 19

monckeberg sclerosis

form of arteriosclerosis characterized by calcific deposits in in medial layer of muscular arteries

Question 20

medial infalmmation

Answer 20

takayasu

giant cell

Question 21

obliterative endarteritis of the vasa vasorum

Answer 21

tertiary syphillis

Question 22

PABA esters

Answer 22

widely used UVB radiation absorbers

O

Question 23

PABA esters

Answer 23

widely used UVB radiation absorbers

Don’t block radiation in UVA wavelength

Question 24

cholestasis

Answer 24

digestive disorer that causes malabsorption and nutritional deficiencies of fat soluble vitamins

Question 25

often occurs in pt w/ prolonged cholestasis

Answer 25

osteomalacia--> vit D def

Question 26

often occurs in pt w/ prolonged cholestasis

Answer 26

osteomalacia--> vit D def

Question 27

brassy barking cough dyspnea hx of URI in child

Answer 27

Croup caused by parainfluenza virus

Question 28

nasal congestion and discharge sneezing cough sore throat

Answer 28

common cold rhino influenza corona

Question 29

URT sxs hoarsness BARKING CouGH AND STRIDOR

Answer 29

parainfluenza

Question 30

sore throate cervical lymphadenopathy PSEUDOMEMBRANE

Answer 30

c. diptheriae

Question 31

sore throat DYSPHAGIA DROOLING

Answer 31

h. influenza

Question 32

URT sxs WHEEZING cough

Answer 32

RSV

Question 33

calciviruses

Answer 33

norwalk viral gastroenteritis

Question 34

variable severity of mitochondrial diseases

Answer 34

random distribution of normal and mutated mitochondria between dauther cells during mitosis> some cells w/ healthy mitochondria and others affected by genetic mutation (HETEROPLASMA)

Question 35

Long term acid suppression w/ PPIs can laed to....

Answer 35

increased risk of HIP fx d/t decreased Ca absorption

Question 36

increase vit D catabolism

Answer 36

anticonvulsants

Question 37

decrase estrogen

Answer 37

aromatase inhibotrs | medroxyprogesterone

Question 38

decrease testosteone and estrogen

Answer 38

GnRH agonists

Question 39

decrease bone formation

Answer 39

glucocorticoids unfractionated heparin thiazolidinediones

Question 40

dust particles

Answer 40

reach ALVEOLI taken up by MPHAGES> stimualte CT growth

Question 41

required to release ACh form presynaptic terminal vesicles at the NMJ

Answer 41

influx of extracellular Ca into presynaptic terminal *occurs following neuronal dpeolarization and opening of VG Ca channels

Question 42

FIXED semental loss of UE P and T sensation, UE lower motor neuron signs in setting of scolisois kyphoscoliosis

Answer 42

syringomyelia

Question 43

AR condition accompanied by congenital neurosensory deafness and long QT syndrome> SCD

Answer 43

jervell and Lange Nielsen syndrome

Question 44

initiates extrinsic pathway of apoptosis

Answer 44

FAS receptor

Question 45

mutation in FAS recpetor or FAS ligand

Answer 45

prevents apoptosis of autoreactive lymphocytes> increased risk of autoimmune disorders like SLE

Question 46

mediates AFF limb of cough reflex ABOVE the vocal cords

Answer 46

internal laryngeal nerve *damaged by foriegin bodies lodged in piriform recess that can damage nerve and impair coughreflex

Question 47

mediates AFF limb of cough reflex ABOVE the vocal cords

Answer 47

internal laryngeal nerve *damaged by foriegin bodies lodged in piriform recess that can damage nerve and impair coughreflex

Question 48

erythematous pruritic pauplues vesicles bullae that appear BILATERALLY And SYMMETRICALY one extensor surfaces celiacs

Answer 48

Dermatitis hepetiformis

Question 49

pruritic urticarial plaques that form tesnse bullae common autoimmune disorder in elderly

Answer 49

bullous pemphigoid

Question 50

spontaneous burns of non-rhythmic onjugate eye movements hypotonia myoclonus abdominal mass

Answer 50

Opsoclonus myoclonus syndrome (paraneoplastic) assoc. w/ NEUROBLASTOMA

Question 51

MC extracranial childhood cancer that develoips from neuroblasts in teh adrenal medulla

Answer 51

nueroblastoma

Question 52

associated w/ increased number of copies of N-myc

Answer 52

neuroblastoma

Question 53

palpable flank mass 2-4 years primitive metanephric tissue

Answer 53

wilms tumor

Question 54

clavulanic acid sulbactam tazobactam

Answer 54

beta lactamase inhibitors

Question 55

liquefactive necrosis

Answer 55

complete digestion and removal of necrotic tissue w/ formation of cystic cavity