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Flashcards in Test 39 Deck (49):
1

how do osteocytes exchange nutrients/waste products

gap junctions

2

observed at apices of glandular cells

tight junctions

3

half desmosomes that extend from basal surfaces of keratinocytes in strat sq epi to basal lamina

hemidesmosome

4

penicillinase resistant penicillins

nafcilin
methicillin
oxacillin

5

penicillinase resistant penicillins are MC used to tx infections caused by...

penicillinase producitng stratins of staph

6

commonly used to tx skin/soft tissue infections (folliculitis, abscesses) for which s. aureus is usual cause

Nafcillin

7

displayed by APC

class II MHC

used to present Ag that (dendrites, Mphates, B lymphocytes ) have encoutered in body

8

neuroleptic malignant syndrome

rigidity
myoglobinuria
autonomic instability
hyperpyrexia

NO myoclonus/presence of rigidity

9


tx for NMS

dantrolene
D2 agonists (bromocriptine

10

NMS

Fever
Encephalopathy
Vitals unstable
Enzymes increased
Rigidity of muscles

11

felling of restlessness/objective motor restlessness

akathisisa

12

chronic, dose related movement disorder that manifests as persistent lip smaking or rhythmic tongue/chwing movements

tardive dyskiniesia

**occurs after long term antipsychotic use

13

when does LV free wall rupture usually occur

3-7 days after onset of MI when coagulative necrosis and neutorphil infiltration have weakened the infarcted myocardium

14

MCC of inhospitdal death d/t MI

LV failure/cardiogenic shock

15

4 days after MI pt presents w/ profound hypotension and shortness of breath
heart sounds are muffled
JVD elevaed

free wall rupture>
cardiac tamponade

16

MCC of death in hospitalized pts after MI

ventricular failure (cardiogenic shock)

17

most frequent complication of fribrinolytic tehrapy

bleeding

18

biceps reflex

C5/C6

19

innervates flexor muscles of arm

sensory to lateral forearm

musculocutaneous

20

sensation to posterior arm/forearm and dorsum of hand

radial nerve (PCN)

21

sensation to medial forearm

ulnar nerve

22

sensation to detloid/lateral arm

axillary

23

COPD affects FEV1/FVC

decreases

(increased lung volumes)

24

restrictive lung disease affects
FEV1/FVC

increases

(reduced lung volumes)

25

nitrates:
nitroglycerin
isosorbide dinitrate
isosorbide mononitrate

VENODILATORS

cause a DECREASE in cardiac work by DECRASING left ventricular filling volume/preload (muscles don't need as much blood/O2 to pump)

26

autoimmune response against pancreatic beta cells that leads to progressive loss of beat cell mass

T1D

*infiltration of islets by inflammatory cells (insulitis) is more prominent in EARLY phases of disease

27

MODY

AD-Genetic defect in insulin secretion

impaired glucose sensing /insulin secretion

28

Neonates infected w/ HBV

often get from moms who are positive for HBsAg and HBeAg

mildly elevated liver enzymes
high risk for chronic infections

viral replication occurs rapidly d/t weak immune system in newborns

29

infant w/
HBsAg
HBeAG
and mildly elevated liver enzymes

HBV

30

Na blocking effects intensify as heart rate increases d/t less time between AP for mediation to dissociate from recpetor

IC

flecainide
propafenone

31

limits maximal heart rate achieved

B1 blockers

32

Antiarrythmics that DONT affect QRS

beta blockers
digoxin
Dofetilide
verapimil

33

Ca channel blocker taht slows SA and AV node conduction
increases coronary blood flow> reduced myocardial O2 demand

verapamil

34

essential in PKU

tyrosine

can no longer be synthesized

35

enz def in PKU

pneylalanine hydroxylase

36

yperactivity
tremor
seizures
blue eyes
fair skin
mousy body odor

PKU

37

B1 receptors location

found in cardiac tissue and on renal JG cells but NOT on vascular smooth msucle

38

B1 blocakde

decrease in cAMP

39

abdominal pain
rectal bleeding
BLIND POUCH connected to ilelum w/ fibrous band attaching to umbilicus

meckels

40

true diverticulum that is often composed of acid secreting gastric mucosa

meckels

41

neuron responding to irreversible injury

red neuron

evident 12-24 hrs after injury

42

shrinkage of cell body
eosinophilia
pyknosis (shirking) of nucleus
loss of nissle substance

red neuron

43

loss of axon

Axonal reaction

enlargement of cell body
eccentric nucleus
enlargement of nucleous
dispersion of nissl substance

44

progressive degenerative disease

neuronal atrophy

loss of neurons
reactive gliosis

45

compensatory response to volume overload of aortic regurge

incrase in LV preload (LV EDV) and eccentric left ventricular hypertrophy

46

tabes dorsalis and argyll robertson pupils

tertiary neurosyphillis

47

tabes dorsalis

affects dorsal columns and dorsal roots of spinal cords> loss of position and vibration sesnse

48

CMV infection in immunocompetent

subclinical infection
possible mononucleosis like syndrome that is monospot negative

49

what must be equal between the pulmonary circualtion and systemic circulation at ALL times

rate of blood flow

must be the same to provide continuous blood flow