Test 50 Flashcards

1
Q

nonlactose fermenting
oxidase +
gram - rod
grapy fruity odor

A

Pseudomonas

Aerobic
Motile!

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2
Q

MCC of MOE, infection of the ear seen in elderly diabetic pts

A

Pseudomonas

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3
Q

oxidase +
gram -
comma shpaed rod
grows on alkaline medium that kills most organisms

A

v. cholerae

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4
Q

gram - rods

fast lactose fermenters

A

klebsiella

e. coli

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5
Q

gram _ lactose non fermenting
oxidase -
non motile
rod shapped

A

shigella

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6
Q

requires and V for growth

A

Haemophilus influenza

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7
Q

signaling pathway for anti-apoptosis, cellular proliferation and angiogenesis

A

PI3K/AKtm/mTOR

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8
Q

What happens to to TK activated mTOR?

A

it translocates to the nucleus

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9
Q

how do you treat a pt who has OD’ed on beta blockers

A

glucagon> increases HR and contractility independent of adrenergic receptors

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10
Q

why can glucagon be used to tx a beta blocker overdose?

A

activates GPCR on cardiac myocytes>
activation of AC>
raises intracellular cAMP>
Ca relase from intracellular stores and SA node firing

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11
Q

why can glucagon be used to tx a beta blocker overdose?

A

activates GPCR on cardiac myocytes>
activation of AC>
raises intracellular cAMP>
Ca relase from intracellular stores and SA node firing

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12
Q
baby w/ hypotonia
poor feeding
jaundice
macroglossia
constipation
umbilical hernia
A

congenital hypothyroidism

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13
Q

standard tx for n gon

A

ceftriaxone

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14
Q

tx for c. trachomatis

A

axithromycin

doxycycline

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15
Q

hilar adenopathy
pulmonary infiltrates
non-caseating lung granulomas in AA female

A

sarcoidosis

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16
Q

what forms granulomas

A

Th1>
IL-2 >
IFNy» stimulates Th1 proliferation and mphage activation

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17
Q

damage to the radial nerve

A

wrist drop

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18
Q

affects opposition of thumb

A

median

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19
Q

limits thumb addduction

A

deep branch of ulnar

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20
Q

limits finger abduction

A

recurrent branch of median nerve

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21
Q

limits hand flexion

22
Q

forms the IVC @ L4/L5

A

L and R common iliac veins

23
Q

what happens hwen ATP binds myosin

A

release of myosin haead from binding site on actin filament

24
Q

what causes renal osteodystrophy

A

end stage renal diseaes>
hypocalcemia and decreased phosphate excretion and decreased renal synth of vit D

*hypocalcemia nad hyperPTH contribute to renal osteodystrophy

25
what causes renal osteodystrophy
end stage renal diseaes> hypocalcemia and decreased phosphate excretion and decreased renal synth of vit D *hypocalcemia nad hyperPTH contribute to renal osteodystrophy
26
How has acute RF been reduced in industrialized nations
tx s. pharyngitis w/ antibiotics
27
acute acalculous cholecysitisis
acute inflammation of GB in abscence of gallstones (often occurs secondary to GB stasis and ischemia) *commonly seen in hospitalized and very ill
28
What is shown to SLOW the progression of HF and reduce all cause mortality in pts w/ CHF
Beta blockers slow ventricular rate and decrease afterload
29
What is specifically used to tx pts w/ HF and CHF?
Carvedilol antagonizes B1/B2 and alpha 1
30
loop diuretic used to tx HF assoc w/ peripheral edema
furosemide/ loop diuretics
31
used to tx supraventricular and ventricular arrhtymias
amiodorone
32
PDE inhibitor that increases cardiac contractility and decreases preload and afterload
milrinone
33
improves morbidity but not mortality in pts w/ CHF
digoxin
34
how do you dx acute cholecystiitis?
often cuased by gallstones obstructing cystic duct identify signs of GB inflammation
35
how do you dx acute cholecystiitis?
often cuased by gallstones obstructing cystic duct identify signs of GB inflammation using US
36
what do you do if US is inconclusive for acute cholecystitis?
NM scan can be used to detect it w/ a radiotracter. GB won't be visulaized d/t obstruction
37
what causes drug induced parkinsonism
D2 receptor blockers Antipsychotics (first generation) Antiemetics
38
how do you tx drug induced parkinsonism
benzotropine (antimuscarnic) | amantadine (increass Da release and prevents reuptake)
39
what is contraindicated for anti-psychotic induced parkinsonism b/c they can preceipitate psychosis
levodopa and | Da agonists
40
tinnitus vertigo sensorineural hearing loss d/t increased volume and pressure of endolymph in hte vestibular apparatus
Menieres disease
41
leads to formation of an annular pancreas
abnormal migration of ventral pancreatic bud *encircles descending part of duodenum> lead to sxs of duodenal obstruction in neonates
42
leads to formation of an annular pancreas
abnormal migration of ventral pancreatic bud *encircles descending part of duodenum> lead to sxs of duodenal obstruction in neonates
43
what is the pancreas derived from
foregut
44
pathogenesis of Wilsons disease
excess of non-ceruloplasmin bound serum copper> | leads to injurious accumulation of this element in the liver, CNS, lenticular nucleus, cornea
45
tx for Wilsons disease
chelation therapy w/ penicillamine to remove excess losely bound serum copper
46
chelating agents used to tx lead poisoning
Dimercaprol | EDTA
47
used to tx cirrhosis related hepatic encephalopathy
lactulose
48
Deferoxxamine
tx hemochromatosis | Fe chelating agent
49
characteristics of intravascular hemolytic anemias
shistocytes d/t fragmented RBC> decreased haptoglobin increased LDH and bilirubin
50
decreased haptoglobin
haptoglobin binds FREE Hb and is indicative of hemolysis
51
gliosis
proliferation of astrocytes in area of neuron degeneration> leads to formation of glial scar which compensates for volum loss after neuronal death