Test 71 Flashcards

(33 cards)

1
Q

46 xx genotype

A

COMPLETE ROLE
ovum loses its maternal chromosomes and then becomes fertilized by a haploid sperm> duplication of the paternal genetic component> 46 XX

size greater than dates
high BCG levels

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2
Q

synringomyelia

A

bilateral loss of P/T

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3
Q

HIgh intraplaque activity of what enzyme can predispose a pt to MI?

A

plaque stability depends on mechanical strenght of overlying fibrous cap

inflam mphages in the intimacan reduce plaque stability by secreting metalloproteinases which degrade collagin!

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4
Q

Ventromedial hypo nuclei

A

satiety center
regulates food INTAKE

lesion> hyperphagia/aggressive behavior

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5
Q

Lateral nuclei

A

hunger

lesion> lose desire to eat

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6
Q

decreases LDL

A

statins

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7
Q

decrease TGs

A

Fibrates:
gemifibrozil
fenofibrate

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8
Q

increase HDL

A

Niacin

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9
Q

Common cause of secondary hyperPTH

A

chronic renal failure

HIGH PTH
low Ca
high phosphate
low calcitriol

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10
Q

calcitriol

A

increases Ca and pohosphate absorption> chronic renal disease> decreased calcitriol>
decrsaed Ca absorption and increased Ca loss in the urine

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11
Q

presents as gross hematuria in an elderly man

A

transitional cell carcinoma

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12
Q

RF for developing transitional cell carcinoma

A
smoking
exposure to rubber 
plastics
aromatic amine containing dyes
textiles
lether
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13
Q

ETEC

A

produces heat labile (LT, choleragen like) and heat stable (ST) enterotoxins

LT>
actiavte AC>
incrased cAMP

ST> GC> increased cGMP

watery diarrhea

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14
Q

CSF from third to fourth ventricle

A

cerebral aqueduct

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15
Q

obstrutction foramen of monro

A

enlargement of lateral ventricle

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16
Q

obstruction of magendie and luschka

A

enlargement of all 4 ventricles

17
Q

phase 0 depolarization

A

inward flux of Ca

18
Q

transmural ischemia of hte inferior wall of the left ventricle> ST elevation in leads II, III, aVF and sinus node dysfxn

19
Q

anteroseptal transmural ischemia

ST elevations in V1-V4

20
Q

transmural ischemia of lateral wall of the ventricle w/ ST eleevations in V5, V6 and possibly I and aVL

21
Q

Thiopental

A

short acting barbituate used for induction anesthesia

after equilibration with the brain it rapidly redistributres into skeletal muscles nad adipose tissue

22
Q

excessive matrix metalloproteinase activity and myofibroblast accumulation in the wound margins

A

contracture>
deformities of wound and surrounding tissues

*palms, soles, anterior thorax, serious burn sites

23
Q

35 y/o M
nontender cervical lymphadenopathy
aggregates of packed follicles that obscure normal LN architecture

A

follicular lymphoa

24
Q

translocation associated w/ follicular lymphoma

A

t(14;18)

overexpression of antiapoptotic gene product, BCL-2

25
BCR-ABL rearrganement t(9;22) | myeloproliferative!!
CML--> constituively active protein tyrosine kinase
26
overexpresion of n-MYC protooncogene
neuroblastoma | SCC of lung
27
hydrocephalus intracranial calcifications chorioretinitis
congenital toxoplasmosis
28
small cardiac valvular vegetations on either side of valve resulting in fibrotic valve thickening and deformity
Libman Sacks endocarditis | occurs in up to 25% of pts w/ sLE
29
tx of choice for uncomplicated malaria
chloroquine
30
added to chloroquine tx for malaria to tx intrahepatic stages of malarial species
primaquine p. vivax p. ovale
31
diuretic that cuases hyponatremia and hypercalcemia
thiazides
32
diuretic that causes hypOcalcemia
loops
33
helpful in early identification of onset of DIC in high risk pts
fibrinogen and platelet count LOW fibrinogen thrombocytopenia