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Flashcards in Test 33 Deck (30):
1

Tx for LOC brought about by severe hypoglycemia

Glucagon

Increases hepatic glycogenolysis and gluconeogenesis stopping hypoglycemia

2

SCD pt
fever
exquisite thigh pain
bacteriemia

Salmonella osteomyelitis

3

nonlactose fermenting
oxidase negative
motile grame negative with special Vi capsule
Endotoxin

Salmonella

Vi capsule protects it from opsonization and phagocytosis

4

toxins that inactivate the 60S ribosome by remvooing adenine from rRNA

shigella (shiga toxin)
EHEC- SLT

5

inactivate EF2

C. diptheriae
p. areguinosa

6

empiric treatment of coagulase negative Stpah

Vancomycin

7

methicillin susceptibile isolate of caog negative stpah infeciton

swith to nafciliin
oxacillin

8

class of antiarrhythmics that demonstrate the most use dependence and class that has the least

1C> 1A>1B

channels spend less time in resting state

9

use dependence

higher rates of depolarization lead to incrased Na channel blockade d/t channels spending LESS time in the resting state

10

1A

Disopyramide
Procainamide
Quinidine

11

1B

Lidocaine
Mexiletine

12

1C

Flecainide
Propafenone

slowly dissociate so blocking effect accumulates over multiple cardiac cycles

13

drugs taht bind and block activated and inactivated VG Na channels in cardiac pacemaker cells and mycocytes

class 1 antiarrhythmics

14

First line therapy for chronic asthma

has the strongest and most predicatable effect on inflammatory component of asthma

corticosteroid

Fluticasone
budesonide

inhibit synthesis of all cytokines

15

how to inactivate HAV

water chlorination
bleach
formalin
UV
boiling for 1 minute

16

pure opoid receptor antagonist used for treating opoid intoxication/overdose

has greatest affinity for mu receptors

Naloxone

17

reverses both CNS and periopheral sxs of SEVERE ATROPINE toxicity

physostigmine (phyxes atropine OD)

18

atropine

BLOCKS Ach receptors (antimuscarinic)

19

physostimine

inhibits AChesterase to increase Ach availabiilty and counteract atropin blockade

20

rapid plasma decay of thiopental

redistribution of drug to other tissues in the body

21

what type of monitoring needs to be done w/ cloazpine

WBC monitoring

22

acute management of venous thrombosis or thromboembolism

heparin

activates antithrombin III

23

contains transmembrane domains composed of alpha helices w/ hydrophobic AA residues like Valine, Alanine
isoleucine, methionine
phenylalanicne

integral membrane proteins that span the cellular membrane

24

binds and inhibits viral DNA/RNA pol and HIV RT inhibitor that DOES NOT requie activation by viral kinase

Foscarnet

25

sialic acid analogue inhibitor of influenza A and B virus neuraminadase

oseltamivir

26

saquinavir

protease inhibitor that binds to catalytic site of HIV aspartic protease and prevents cleave of polyprotein precursors

27

cytosine anallog that is a NRTI that must be phosphorylated to its active form

lamivudine

28

polymorphic QRS complex that chagnes in amp and legnth

ECG

29

Antiarrhythmic agents that cuase torsades

kPDQ

aIDS

30

protease inhibitor that causes hyperglycemia, lipodystrophy, inhibits p450

indinavir