Test 70 Flashcards by Sarah Carlson

leading cause of cancer mortality in women

lung cancer

increased cigarette smoking

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IL-2

stimulates grwoth of CD4 adn CD8 and B cells

also activates NK cells and monocytes (anti-cancer effect on metastatic melanoma and arenal cell carcinoma)

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uniform thickening of the ventricular wall and narrowing of the ventrcicular cavity

concentric hypertrophy

seen w/ increased afterload

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dilation of ventricle w/ associated increase in chamber size

volume overload

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thalamic syndrome

total sensory loss on CONTRALATERAL side of hte body

*no motor deficits

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lesion of internal capsule

motor deficit

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ischemic event of the pons

coma
bilateral paralysis
cerecbrate rigidity
pinpoint pupils
death

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small 5 mm cavities in hte basal ganglia, osterior limb of internal capsule, pons aand cerebellum are known as…

lacunar infarctions

d/t occlusion of small penetrating arteries in settin gof HTN or DM

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small vessel lipohyalinosis and atherosclerosis

leads to lacunar infarctions

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oligodendrocyte apoptosis

occurs in MS> demyelinating disease of CNS

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loss of atrail contraction d/t a. fib

reduce LV preload and CO and can cause systemic hypotension

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meconim ileus

specific for CF

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accounts for 80% of eventual deaths d/t CF

tx resistant infectious pneumonias
bronchiectasis
cor pulmonale

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fantasy

immature defense mechanism

substitutes imaginary, less distrubing view of world to avoid awareness of painful feelings

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denial

refuse to acknoweldge a painful reality

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Total resistance for vessels in parallel

1/ sum of inverse values for resistance

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component of normal colonic and urogenital flora
grows in hypertonic saline and bile
gamma hemolytic
catalase negative
Pyrrolidonyl arylamidase positive

entercoccs

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OPT resistant
bile insoluble

dental caries
SBE after dental work

s. viridans

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opt sensitive
bile soluble

pneumonia
meningitis
otitis medai

s. pneumo

PYR +
bac sensitvite

cellulitis
pharyngitis
ersipelas

GAS

PYR neg
CAMP pos

neonatal sepsis
pneumonia
meningitis
UTI

GBS

grows in bilea nd 6.5 % na CL
PYR +

IE after GU procedures

enteroccoci

gows in BILE but nOT NaCL
PYR _

IE assoc w/ CRC

strep bovis

phenoxybenzamine

irreversible A1 and A2 adrenergic antagonist

HIGH conc of NE can overcome effect

Acyclovir valacyclovir famciclovir ganciclovir

nucleoside analogues that require both herpes viral and cellular kinases for conversion to active nucleoside triphosphate form

cidofovir | tenofovir

nucleoTide monophosphate requires ONLY cellular kinases fora ctivation

cell dep nucleosides

zidovudine | lamivudine

drug induced lupus

linked to drugs that aremetabolized by N acetylation in the liver (hydralazine, procainamide)

nitroprusside

short acting | venousa nd arterial VASODILATOR that decreass both preload and afterload

produces eggg shell calcifications of hilar nodes and birefringent particles surrounded by fibrous tissues

silicosis

calcified pleural plauqes and FERRUGINOUS bodies

asbestosis

non caseating granulomas

berylliosis and hypersensitivitiy pneumonitis

perilymphatic accumulations of coal dust laden mphages

coal miners lung

pure red cell aplasia

severe hypoplasia of marrow erythroid elements in setting of normal granulopoiesis and thrombopoiesis assoc. w? thymoma lymphocytic leukemias parvo B19

coadministartion of SSRIsa nd MAO inhbitors

can produce excessive synaptic 5HT levels secondary to decreased reuptake and decrased degradation> 5HT syndrome

cuase of claudication

ahtersclerosis of larger arteries

NSAID assoc chronic renal injury

papillary necrosis chronic interstitial nephritis only seen in advanced stages common in pts suffering from chronic pain

vit A def

causes night blindness fat soluble vitamin malabsorption (chronic cholestasis from biliary obstruction)

decreased exposure to sunlight

vit D def

strict vegetarian diet

cobalamin def

chronic renal faliure

itching d/t uremia

chronic hemolytic anemia (sickle cell)

retinopathy d/t relative ischemia

pts bleed coagulation cascade is activated PT and PTT are prlonged low fibrinogen and increased FDP

DIC

TTP-HUS

do not bleed only platelts activated normal PT nad PTT normal fibrinogen

HFE protein mutaiotns> decreased hepcidin synthesis> increased DMT1 expression by enterocytes> Fe overload

primary hemochromatosis at incrased risk for cirrhosis and hepatocellular carcinoma

scabies

highly contagious pruritic rash flexor surfaces dx w/ skin scrapings