Chemistry of Life Flashcards Preview

Fundamentals of Molecular Medicine > Chemistry of Life > Flashcards

Flashcards in Chemistry of Life Deck (64):
1

 

 

 

Fundamentals of Molecular Medicine

 

1. DNA Synthesis and Function

2. RNA Synthesis and Function

3. Protein Synthesis and Function

4. Membrane channels & Ionic Movements

5. Receptors and Signal Transduction

6. Genetic Past & Genetic Future

2

 

 

 

Fundamental of Cellular Medicine

3

 

Matter

Proteins

Nucleic Acids

Phospholipids

ATP

4

 

 

 

Electrons

5

 

 

 

Ionizing Radiation

6

 

 

 

Another form of Ionizing Radiation 

7

 

 

Ionizing Radation in Medicine

8

 

 

 

Ultraviolet Radiation

Effect of UV Radiation

9

 

 

 

How much is one mole?

10

 

 

 

What is one molar?

11

 

 

 

Electrons, Protons, and Atomic Weight

12

 

 

 

One Molar of NaCl

13

 

 

 

0.14 molar NaCl

14

 

 

Normal Serum Electrolyte Reference Ranges "normal ranges"

15

 

 

 

mmols vs. mEq

16

 

 

 

What unit are Albumin Levels?

17

 

 

 

What unit to describe calcium levels

18

 

 

 

What unit describes glucose levels

19

 

 

 

What 2 units describes ethanol levels?

20

 

 

 

Equation for pH

21

 

 

Describe the significance of pH=0 and pH=14

22

 

 

 

Describe the basicitiy and acidity of common household items.

Describe in words what pH means.

23

 

 

 

What are the elements that comprise the human body?

24

 

 

 

What elements lead to pathology in humans?

25

 

 

 

What elements are used to treat disease?

26

 

 

 

Where are proteins mainly found?

27

 

 

What are the functions of proteins and what tasks do they perform in the human body?

28

 

 

 

Variation in size of proteins

29

 

 

 

Examples of Different Proteins related to their tasks

30

 

 

 

Enzyme Hexokinase

31

 

 

 

Transcription Factor

32

 

 

 

Structural Classifications of Proteins

33

 

 

 

Secondary Structure

34

 

 

 

Interactions comprising secondary structure

35

 

 

 

Primary structure. Which terminus comes first?

 

 

 

Amino acids

36

 

 

 

Primary structure is comprised of which atoms?

37

 

 

 

How are amino acids classified/distinguished?

38

 

 

 

Draw out Amino-Terminus and Carboxy Terminus and their correct order.

39

 

 

Which components join together to form proteins?

What is this process called and what drives it?

40

 

 

 

Relative to the protein where do many hydrophobic amino acids find themselves?

41

 

 

 

Role of hydrophobic amino acids

42

 

 


What is cysteine and what is its role/function?

43

 

 

 

Draw out Cysteine forming a Disulfide bond

44

 

 

What is the charge of Aspartate?

45

 

 

 

What is the charge of lysine?

46

 

 

 

What type of interaction do amino acids like aspartate and lysine exhibit?

47

 

 

 

Draw serine out and what functional group does it contain?

48

 

 

 

Explain the process and significance of phosphorylation.

49

 

 

 

What is the significance of kinases and phosphatases? What are the outcomes of their activity?

50

 

 

What are catalysts?

What is their role regarding the transition state?

Where are they generally located?

51

 

 

 

What levels of protein structure do enzymes often exhibit?

52

 

 

 

Where does a substrate bind?

53

 

 

 

Describe the induced fit model and its subsequent feedback inhibition

54

 

 

 

Explain competitive product inhibition

55

 

 

 

Allosteric site and allosteric activator/inhibitor

56

 

 

 

Multiple levels of regulation in metabolic pathways

57

 

 

 

Draw a model of allosteric activation/inhibition

58

 

 

 

What is a co-factor?

59

 

 


What elements make up enzymes?

60

 

 

 

Coenzymes

61

 

 

 

Coenzymes in telomerase formation

62

 

 

 

What are nucleic acids and where do they generally make proteins?

63

 

 


Role of Phospholipids

64

 

 

 

Role of ATP

Decks in Fundamentals of Molecular Medicine Class (77):