Fundamentals of Molecular Medicine
1. DNA Synthesis and Function
2. RNA Synthesis and Function
3. Protein Synthesis and Function
4. Membrane channels & Ionic Movements
5. Receptors and Signal Transduction
6. Genetic Past & Genetic Future
Fundamental of Cellular Medicine
Another form of Ionizing Radiation
Ionizing Radation in Medicine
Effect of UV Radiation
How much is one mole?
What is one molar?
Electrons, Protons, and Atomic Weight
One Molar of NaCl
0.14 molar NaCl
Normal Serum Electrolyte Reference Ranges "normal ranges"
mmols vs. mEq
What unit are Albumin Levels?
What unit to describe calcium levels
What unit describes glucose levels
What 2 units describes ethanol levels?
Equation for pH
Describe the significance of pH=0 and pH=14
Describe the basicitiy and acidity of common household items.
Describe in words what pH means.
What are the elements that comprise the human body?
What elements lead to pathology in humans?
What elements are used to treat disease?
Where are proteins mainly found?
What are the functions of proteins and what tasks do they perform in the human body?
Variation in size of proteins
Examples of Different Proteins related to their tasks
Structural Classifications of Proteins
Interactions comprising secondary structure
Primary structure. Which terminus comes first?
Primary structure is comprised of which atoms?
How are amino acids classified/distinguished?
Draw out Amino-Terminus and Carboxy Terminus and their correct order.
Which components join together to form proteins?
What is this process called and what drives it?
Relative to the protein where do many hydrophobic amino acids find themselves?
Role of hydrophobic amino acids
What is cysteine and what is its role/function?
Draw out Cysteine forming a Disulfide bond
What is the charge of Aspartate?
What is the charge of lysine?
What type of interaction do amino acids like aspartate and lysine exhibit?
Draw serine out and what functional group does it contain?
Explain the process and significance of phosphorylation.
What is the significance of kinases and phosphatases? What are the outcomes of their activity?
What are catalysts?
What is their role regarding the transition state?
Where are they generally located?
What levels of protein structure do enzymes often exhibit?
Where does a substrate bind?
Describe the induced fit model and its subsequent feedback inhibition
Explain competitive product inhibition
Allosteric site and allosteric activator/inhibitor
Multiple levels of regulation in metabolic pathways
Draw a model of allosteric activation/inhibition
What is a co-factor?
What elements make up enzymes?
Coenzymes in telomerase formation
What are nucleic acids and where do they generally make proteins?
Role of Phospholipids
Role of ATP