Pharmacokinetics Pt. I Flashcards Preview

Fundamentals of Molecular Medicine > Pharmacokinetics Pt. I > Flashcards

Flashcards in Pharmacokinetics Pt. I Deck (33):
1

 

 

 

What is Pharmacokinetics?

A image thumb
2

 

 

 

Why is pharmacokinetics important?

A image thumb
3

 

 

 

4 Equations

A image thumb
4

 

 

 

One Compartment Model

A image thumb
5

 

 

 

Two Compartment Model

A image thumb
6

 

 

 

Linear Plot of Drug Concentration vs. Time

A image thumb
7

 

 

 

Semi-Log Plot of Drug Concentration vs. Time

A image thumb
8

 

 

 

Apparent Volume of Distribution Equation 

A image thumb
9

 

 

 

Apparent Volume of Distribution Definition 

A image thumb
10

 

 

 

Vd and Tissue vs. Plasma Binding

A image thumb
11

 

 

 

Patients and Vd

A image thumb
12

 

 

 

Parameters for Drug Correction 

A image thumb
13

 

 

 

Skin and Estimating Vd

A image thumb
14

 

 

 

Obese Patients vs. Patients with Edema

A image thumb
15

 

 

 

[Drug] vs. Time and First Order Kinetics

A image thumb
16

 

 

 

Elimination Rate Constant Equation 

A image thumb
17

 

 

 

Drug with 0 Order Kinetics 

A image thumb
18

 

 

 

First Order Kinetics vs. Saturating Kinetics (0 Order Kinetics)

A image thumb
19

 

 

 

Clearance Equation 

A image thumb
20

 

 

 

Definition of Clearance

A image thumb
21

 

 

 

Fast Acetylators vs. Slow Acetylators

A image thumb
22

 

 

 

Affect of Clearance on Age

A image thumb
23

 

 

 

Bioavailability Equation 

A image thumb
24

 

 

 

Definition of Bioavailability 

A image thumb
25

 

 

 

3 Important Parameters of Oral Drug Concentration 

A image thumb
26

 

 

 

Bioequivalence 

A image thumb
27

 

 

 

Bioequivalence vs. Bioavailability 

A image thumb
28

 

 

 

Absorption and Half Life

A image thumb
29

 

 

 

Approach to Solving PK Problems

A image thumb
30

Q image thumb

A image thumb
31

Q image thumb

A image thumb
32

 

 

 

Determine Vd and K

Q image thumb

A image thumb
33

 

 

 

Clearance Definition 

A image thumb

Decks in Fundamentals of Molecular Medicine Class (77):