Humoral Immunity Flashcards Preview

Fundamentals of Molecular Medicine > Humoral Immunity > Flashcards

Flashcards in Humoral Immunity Deck (34):
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Effector Functions of Ig Classes

 

Most Abundant  = IgG = workhorseIgD and IgE are rarest.

Immunity to fetus — IgG

IgM always expressed first

IgG expressed during memory response    Mucosa is IgA

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[Antibody] vs. Time After Immunization

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IgM vs. IgG after First Exposure

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IgG

Opsonization = IgG

Complement = IgM and IgG

Hypersensitivity = IgE  FC Receptors = Mass Cells and Basophils express them

IgD

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IgA = Respiratory tract

Anaphylaxis = IgE 

IgG Convalescent patient

IgA is Breast feeding

Complement = IgG 

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Process of Opsonization?

Ig Class?

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What Ig are involved in Opsonization?

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10

11

 

 

 

Fraction of Adult Level of Serum Immunoglobulins

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Affinity of IgM vs. IgG

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Physiological Roles of Ag-Ab Interaction

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Neutralization 

15

 

 

 

FC Receptors

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IgE Role in Allergies

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Immediate Hypersensitivity 

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Antibody Isotype and Effector Functions

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Affinity vs. Avidity 

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IgM vs. IgG Affinity vs. Avidity 

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Ag-Ab Complex Formation 

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Antibody Titer

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What is the Antibody Titer?

 

 

 

This is a titer for 1:512

24

 

 

 

Elisa

 

 

Elisa Assay. You’re looking for antibody against organisms.

You coat the well with HIV protein. 

Add Test Antiserum

25

 

 

 

Western Blot

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Isohemagluttinins

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Blood Typing 

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Rh Disease

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30

 

 

Coombs Test

 

Indirect Coombs Test

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Direct vs. Indirect Coombs Test

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Coombs Reagent

 

and 

 

RhoGAM

34

 

 

Isohemagglutinins are IgM class which doesn’t cross the placental barrier so you don’t have those types of problems. 

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