Humoral Immunity Flashcards by Omar Saqr

Q

Effector Functions of Ig Classes

A

Most Abundant = IgG = workhorseIgD and IgE are rarest.

Immunity to fetus — IgG

IgM always expressed first

IgG expressed during memory response Mucosa is IgA

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Q

[Antibody] vs. Time After Immunization

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Q

IgM vs. IgG after First Exposure

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Q

A

IgG

Opsonization = IgG

Complement = IgM and IgG

Hypersensitivity = IgE FC Receptors = Mass Cells and Basophils express them

IgD

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Q

A

IgA = Respiratory tract

Anaphylaxis = IgE

IgG Convalescent patient

IgA is Breast feeding

Complement = IgG

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Q

Process of Opsonization?

Ig Class?

A

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Q

What Ig are involved in Opsonization?

A

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Q

Fraction of Adult Level of Serum Immunoglobulins

A

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Q

Affinity of IgM vs. IgG

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Q

Physiological Roles of Ag-Ab Interaction

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Q

Neutralization

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Q

FC Receptors

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Q

IgE Role in Allergies

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A

Q

Immediate Hypersensitivity

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A

Q

Antibody Isotype and Effector Functions

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A

Q

Affinity vs. Avidity

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A

Q

IgM vs. IgG Affinity vs. Avidity

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A

Q

Ag-Ab Complex Formation

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A

Q

Antibody Titer

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A

Q

What is the Antibody Titer?

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A

This is a titer for 1:512

Q

Elisa

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A

Elisa Assay. You’re looking for antibody against organisms.

You coat the well with HIV protein.

Add Test Antiserum

Western Blot

Isohemagluttinins

Blood Typing

Rh Disease

Coombs Test Indirect Coombs Test

Direct vs. Indirect Coombs Test

Coombs Reagent and RhoGAM

Isohemagglutinins are IgM class which doesn’t cross the placental barrier so you don’t have those types of problems.