Innate Immunity

Question 1

What ab’s activate complement?

Answer 1

Question 2

Effector Functions of Complement

Answer 2

Question 3

Physiological Activities of Complement

Answer 3

Question 4

Opsonization by C3B

Answer 4

Question 5

Immune Adherence vs. Opsonization

Answer 5

Question 6

What mechanism protects against tetanus Toxin?

Answer 6

Neutralization

Question 7

What is the major role of complement?

Answer 7

Major Role of Complement is actually inflammation not the lysis aspect

Question 8

Anaphylatoxins

Answer 8

activate mast cells to release histamines

Question 9

What is the most powerful attractant for Neutrophils?

Answer 9

C5a is the most powerful attractant for neutrophils

Question 10

What is an important aspect of F-Met in bacteria?

Answer 10

F-Met is another attractant

Question 11

What is the role of Anaphylatoxins?

Answer 11

Question 12

3 Major Roles of Complement

Answer 12

Question 13

C3 Convertase

Answer 13

Common to both Alternate and Classical Pathway of Complement?

Question 14

Describe the function of C3 Convertase

Answer 14

Question 15

How is C5 Convertase made and what is it’s function?

Answer 15

Question 16

What opsonins are part of the MAC Complex?

Answer 16

Question 17

Overview of Formation of MAC

Answer 17

Question 18

Roles of C5-C9

Don’t memorize just Read.

Answer 18

Question 19

Desribe the overall pathway that is common to complement

Answer 19

Question 20

1st Step of the Classical Pathway

Answer 20

Question 21

2nd Step of the Classical Pathway

Answer 21

Question 22

Complement Fixation

Answer 22

Question 23

Describe the Steps of the Alternate Pathway

Answer 23

Question 24

Stabilization of Alternate C3 Convertase

Answer 24

Question 25

Properdin

Answer 25

Question 26

Overview of All 3 Pathways

Answer 26

Question 27

Comparision of All 3 Pathways

Answer 27

Question 28

C1 Esterase Inhibitor and Decay Accelerating Factor

Answer 28

Question 29

Deficiencies in Classical Pathway

Answer 29

Question 30

DAF Deficiency C3 Deficiency and C5-C8 Deficiency

Answer 30

Question 31

Peroxysmal Nocturnal Hemoglobinuria

Answer 31

Question 32

Table of Complement Proteins and Effects of their Deficiency

Answer 32

Question 33

Overview of Complement showing where DAF and C1Esterase deficiencies are

Answer 33

Question 34

Answer the Following Questions

Answer 34

Question 35

True or False

Answer 35