Innate Immunity Flashcards Preview

Fundamentals of Molecular Medicine > Innate Immunity > Flashcards

Flashcards in Innate Immunity Deck (35):
1

 

 

 

What ab's activate complement?

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2

 

 

 

Effector Functions of Complement

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3

 

 

 

Physiological Activities of Complement

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4

 

 

 

Opsonization by C3B

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5

 

 

 

Immune Adherence vs. Opsonization

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6

 

 

 

What mechanism protects against tetanus Toxin?

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Neutralization

7

 

 

 

What is the major role of complement?

 

 

 

Major Role of Complement is actually inflammation not the lysis aspect

8

 

 

 

Anaphylatoxins

 

 

 

activate mast cells to release histamines

9

 

 

 

What is the most powerful attractant for Neutrophils?

 

 

 

C5a is the most powerful attractant for neutrophils

10

 

 

 

What is an important aspect of F-Met in bacteria?

 

 

 

F-Met is another attractant

11

 

 

 

What is the role of Anaphylatoxins?

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12

 

 

 

3 Major Roles of Complement

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13

 

 

 

C3 Convertase

 

 

 

Common to both Alternate and Classical Pathway of Complement?

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14

 

 

 

Describe the function of C3 Convertase

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15

 

 

 

How is C5 Convertase made and what is it's function?

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16

 

 

 

What opsonins are part of the MAC Complex?

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17

 

 

 

Overview of Formation of MAC

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18

 

 

 

Roles of C5-C9 

Don't memorize just Read.

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19

 

 

 

Desribe the overall pathway that is common to complement

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20

 

 

 

1st Step of the Classical Pathway

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21

 

 

 

2nd Step of the Classical Pathway 

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22

 

 

 

Complement Fixation 

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23

 

 

 

Describe the Steps of the Alternate Pathway 

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24

 

 

 

Stabilization of Alternate C3 Convertase

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25

 

 

 

Properdin 

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26

 

 

 

Overview of All 3 Pathways

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27

 

 

 

Comparision of All 3 Pathways

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28

 

 

C1 Esterase Inhibitor

and

Decay Accelerating Factor

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29

 

 

 

Deficiencies in Classical Pathway 

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30

 

 

DAF Deficiency

C3 Deficiency 

and C5-C8 Deficiency

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31

 

 

 

Peroxysmal Nocturnal Hemoglobinuria

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32

 

 

 

Table of Complement Proteins and Effects of their Deficiency

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33

 

 

 

Overview of Complement showing where DAF and C1Esterase deficiencies are

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34

 

 

 

Answer the Following Questions

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35

 

 

 

True or False

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Decks in Fundamentals of Molecular Medicine Class (77):