Innate Immunity Flashcards Preview

Fundamentals of Molecular Medicine > Innate Immunity > Flashcards

Flashcards in Innate Immunity Deck (35):
1

 

 

 

What ab's activate complement?

2

 

 

 

Effector Functions of Complement

3

 

 

 

Physiological Activities of Complement

4

 

 

 

Opsonization by C3B

5

 

 

 

Immune Adherence vs. Opsonization

6

 

 

 

What mechanism protects against tetanus Toxin?

 

 

 

Neutralization

7

 

 

 

What is the major role of complement?

 

 

 

Major Role of Complement is actually inflammation not the lysis aspect

8

 

 

 

Anaphylatoxins

 

 

 

activate mast cells to release histamines

9

 

 

 

What is the most powerful attractant for Neutrophils?

 

 

 

C5a is the most powerful attractant for neutrophils

10

 

 

 

What is an important aspect of F-Met in bacteria?

 

 

 

F-Met is another attractant

11

 

 

 

What is the role of Anaphylatoxins?

12

 

 

 

3 Major Roles of Complement

13

 

 

 

C3 Convertase

 

 

 

Common to both Alternate and Classical Pathway of Complement?

14

 

 

 

Describe the function of C3 Convertase

15

 

 

 

How is C5 Convertase made and what is it's function?

16

 

 

 

What opsonins are part of the MAC Complex?

17

 

 

 

Overview of Formation of MAC

18

 

 

 

Roles of C5-C9 

Don't memorize just Read.

19

 

 

 

Desribe the overall pathway that is common to complement

20

 

 

 

1st Step of the Classical Pathway

21

 

 

 

2nd Step of the Classical Pathway 

22

 

 

 

Complement Fixation 

23

 

 

 

Describe the Steps of the Alternate Pathway 

24

 

 

 

Stabilization of Alternate C3 Convertase

25

 

 

 

Properdin 

26

 

 

 

Overview of All 3 Pathways

27

 

 

 

Comparision of All 3 Pathways

28

 

 

C1 Esterase Inhibitor

and

Decay Accelerating Factor

29

 

 

 

Deficiencies in Classical Pathway 

30

 

 

DAF Deficiency

C3 Deficiency 

and C5-C8 Deficiency

31

 

 

 

Peroxysmal Nocturnal Hemoglobinuria

32

 

 

 

Table of Complement Proteins and Effects of their Deficiency

33

 

 

 

Overview of Complement showing where DAF and C1Esterase deficiencies are

34

 

 

 

Answer the Following Questions

35

 

 

 

True or False

Decks in Fundamentals of Molecular Medicine Class (77):