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Fundamentals of Molecular Medicine > Innate Immunity > Flashcards

Flashcards in Innate Immunity Deck (35)
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1
Q

What ab’s activate complement?

A
2
Q

Effector Functions of Complement

A
3
Q

Physiological Activities of Complement

A
4
Q

Opsonization by C3B

A
5
Q

Immune Adherence vs. Opsonization

A
6
Q

What mechanism protects against tetanus Toxin?

A

Neutralization

7
Q

What is the major role of complement?

A

Major Role of Complement is actually inflammation not the lysis aspect

8
Q

Anaphylatoxins

A

activate mast cells to release histamines

9
Q

What is the most powerful attractant for Neutrophils?

A

C5a is the most powerful attractant for neutrophils

10
Q

What is an important aspect of F-Met in bacteria?

A

F-Met is another attractant

11
Q

What is the role of Anaphylatoxins?

A
12
Q

3 Major Roles of Complement

A
13
Q

C3 Convertase

A

Common to both Alternate and Classical Pathway of Complement?

14
Q

Describe the function of C3 Convertase

A
15
Q

How is C5 Convertase made and what is it’s function?

A
16
Q

What opsonins are part of the MAC Complex?

A
17
Q

Overview of Formation of MAC

A
18
Q

Roles of C5-C9

Don’t memorize just Read.

A
19
Q

Desribe the overall pathway that is common to complement

A
20
Q

1st Step of the Classical Pathway

A
21
Q

2nd Step of the Classical Pathway

A
22
Q

Complement Fixation

A
23
Q

Describe the Steps of the Alternate Pathway

A
24
Q

Stabilization of Alternate C3 Convertase

A
25
Q

Properdin

A
26
Q

Overview of All 3 Pathways

A
27
Q

Comparision of All 3 Pathways

A
28
Q

C1 Esterase Inhibitor

and

Decay Accelerating Factor

A
29
Q

Deficiencies in Classical Pathway

A
30
Q

DAF Deficiency

C3 Deficiency

and C5-C8 Deficiency

A
31
Q

Peroxysmal Nocturnal Hemoglobinuria

A
32
Q

Table of Complement Proteins and Effects of their Deficiency

A
33
Q

Overview of Complement showing where DAF and C1Esterase deficiencies are

A
34
Q

Answer the Following Questions

A
35
Q

True or False

A

Decks in Fundamentals of Molecular Medicine Class (77):