Fibrous Proteins Flashcards Preview

Fundamentals of Molecular Medicine > Fibrous Proteins > Flashcards

Flashcards in Fibrous Proteins Deck (53)
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1
Q

Fibrous Protein

A
2
Q

Collagen

A
3
Q

Collagen and Collagen Related Diseases

A
4
Q

What is the Pathology?

A
5
Q

Pathology?

A
6
Q

Pathology?

A
7
Q

Pathology?

A
8
Q
A
9
Q
A
10
Q

Mutation Underlying Osteogenesis Imperfecta

A
11
Q

Levels of Collagen Structure

A
12
Q

Collagen Role in Bone Formation

A
13
Q

Levels of Collagen Structure Models

A
14
Q

Collagen Primary Structure

A
15
Q

Hydroxyproline

A
16
Q

Collagen Primary Structure and Interchain Hydrogen Bonding

A
17
Q

Model of Tripple Helix

A
18
Q

Stabilizing the Triple Helix

A
19
Q

Roles of Hydroxyproline

A
20
Q

Collagen Synthesis

A
21
Q

Steps in Collagen Biosynthesis

A
22
Q

Function of Collagen Pro-Peptides

A
23
Q

Collagen Pro-Peptides

A
24
Q

Collagen Biosynthesis from transcription to formation

A
25
Q

Hydroxylation of Lysine

A
26
Q

Hydroxylation of Proline

A
27
Q

Why is Ascorbate acid essential in Collagen Biosynthesis

A
28
Q

Role of Hydroxyproline

A
29
Q

Lysine and Proline Hydroxylases

A
30
Q

Scurvy

A
31
Q

Cross-Link Formation in Collagen

A
32
Q

Post translational modification in lysine crosslink formation

A
33
Q

One type of Cross-Link Seen in Collagen

A
34
Q

Collagen Disorders

A
35
Q

Elastin

A
36
Q

What is Elastin

A
37
Q

Major differences between Collagen and Elastin

A
38
Q

Williams Syndrome and Supravalvular Aortic Stenosis

A
39
Q
A
40
Q

Elastin Primary Structure

A
41
Q

Elastin Biosynthesis from transcription to formation

A
42
Q

Entropy Driven Elastic Recoil

A
43
Q

Elastin Open and Closed State

A
44
Q

Elastin Stretching the Limits

A
45
Q

Desmosine

A
46
Q

Building Elastin

A
47
Q

Fibrillin and Fibulin

A
48
Q

Fibrillin 1 Secretion

A
49
Q

Marfan’s Syndrome

A
50
Q
A
51
Q
A
52
Q
A
53
Q

Conclusion

A

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