Body Fluid Spaces Flashcards Preview

Fundamentals of Molecular Medicine > Body Fluid Spaces > Flashcards

Flashcards in Body Fluid Spaces Deck (43):
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Compartmentalization of Fluids

Compartments:

Plasma

Capillary Membrane

Interstitial Fluid

Cell Membrane

Intracellular Fluid

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E. Freezing point depression

It all depends on the number of particles.

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D. Elicits no net water flow from the cells.

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Intracellular Concentrations of Ions

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Intracellular Concentration of Glucose and Proteins

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Total mOsm/L in Plasma vs. Interstitial vs. Intracellular

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Fluid and Body Weight

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Body water content

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Extracellular vs. Intracellular Fluid Content

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Blood Volume vs. Plasma Volume

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Hematocrit

 

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1 - Hct

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Whole Blood Volume 

 

 

 

1-Hct — should be called the Plasmacrit.

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How do you measure a pool?

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Fluid Space Measurement Dye-Dilution Technique

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Measurement of Body Fluid Spaces

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Plasma Markers

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Extracellular Fluid Markers

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Total Body Water Markers (Z) 

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Time to Reach Steady State for Each Compartment

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Water Flow Accross Biological Membranes

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Size and Charge vs. Membrane

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Forces of Water movement

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Osmotic Pressure

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Osmolar Concentration

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Effect of a 150 mM solution of NaCl

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Effective Osomotic Pressure

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Van't Hoff Equation

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Movement of Water accross Capillary

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Colloid Osmotic Pressure

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Ultrafiltration 

 

 

 

filtration using a medium fine enough to retain colloidal particles, viruses, or large molecules.

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Filtration Rate/Starling Equation

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Interstitium and Starling Equation

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Blood Pressure

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Concept of Net Filtration 

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Movement of Water accross Cell Membrane

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D. Plasma Space, Interstitial same and intracellular space would all loose fluid proportionally. 

When we sweat we lose more water than we do salt. So ECF becomes concentrated and water will flow from inside to outside cell. But all 3 would loose water proportionally. 

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B. Most of the water would come from the extracellular space (plasma + interstitial)  Why is this different? Because when we bleed we lost an isotonic fluid so we didn’t create an osmotic imbalance. Therefore there’s no osmotic force that draws out water from our intracellular space. 

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Isotonic vs. Isosmotic

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Solutions and Isosmotic vs. Isotonic

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D. Expansion of both the extracellular space and the intracellular space

 

Glucose get’s taken into the cells very quickly and you end up with a infusion of water with essentially no solute. This is very bad.

Blood cells will undergo hemolysis — RBC’s would explode because they would take in the water.

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