Multifactorial Inheritance Flashcards Preview

Fundamentals of Molecular Medicine > Multifactorial Inheritance > Flashcards

Flashcards in Multifactorial Inheritance Deck (23):
1

 

 

 

Objectives

2

 

 

 

Leading Causes of Death by Age Group

3

 

 

 

What makes complex diseases complex?

4

 

 

 

Why are complex traits Multifactorial 

5

 

 

 

Dichotomous and Continuous Traits

6

 

 

 

Threshold Model of Genetic Susceptibility 

7

 

 

 

Gene Environment Interaction

8

 

 

 

Multifactorial Traits and Twin Studies

9

 

 


Concordance

10

 

 

 

Twins and Type I vs. Type II Diabetes

11

 

 

 

Common Birth Defects

12

 

 

 

Prevelance of Spinal Bfida 

13

 

 

 

Prevention of Neural Tube Defects

14

 

 

 

Population Genetics

15

 

 

 

Punnet Square

16

 

 

 

Hardy-Weinberg Equation

 

 

 

When alleles are in equilibrium the sum of these is 1?

17

 

 

 

Assumptions of Hardy Weinberg Equilibrium 

18

 

 

 

Disease Frequency vs. Allele Frequence

 

 

Disease Frequency is not Allele Frequency

Disease Frequency is q2

But Allele Frequency is P or Q

19

20

 

 

 

Summary of Part I

21

 

 

 

Summary of Key Points Pt. II

22

 

 

 

Summary of Key Points Pt. III

23

 

 

 

Summary of Key Points IV

Decks in Fundamentals of Molecular Medicine Class (77):