DNA Structure Flashcards
(53 cards)
What are the conclusions of this study?
40% of the reasons behind childhood mortality could be due to genetic components.
Genetic Disease are very common. Most common is cancer.
Who discovered Genes are made of DNA?
Oswald Avery
No Nobel Prize though
What are the two sugars in nucleic acids?
Draw them.
Draw the Structure of ATP
How many purines are there?
Draw them.
How many Pyrimidines are there?
Draw them.
What’s the difference between DNA and RNA
RNA has a 2’ Hydroxy group whereas DNA as a 2’ Hydrogen – Makes it more stable/less reactive than RNA
What are the 4 Nucleotides in DNA?
Draw them.
Nucleoside vs. Nucleotide
Nucleoside no phosphate group
Nucleotide has the phosphate group
Ribonucleotides vs. Nucleotides?
How are phosphates linked to a nucleotide?
Orientation of a DNA Segment.
Draw a segment.
What is Chargaff’s Rule?
Hydrogen Bonding Occurs Between..
Which is more stable G-C interactions or A-T? and Why?
When RNA is involved in base pairing
What’s the difference between T and U when it comes to RNA.
T = DNA
U = RNA
Difference between T and U there’s a 5’ methyl Group
How are DNA chains organized
one chain runs 5’ to 3’ and another chain runs 3’ to 5’
Anti-parralel and Opposite Polarity
Model?
Model?
Double Stranded DNA?
Right Handed Helix
Approx. 10 Bp per Turn
Complementary
For every A there must be a T
and for every G there must be a C
Base Pair orientation to helix
Base Pairs are perpendicular to helix
Major Groove
Wide and Shallow
Coding Information is easily accessible
Minor Groove
Narrow and deep
Restricted access to base pairs and information
