Signal Transduction Flashcards
1
Q
Topics
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2
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Fundamentals of Molecular Medicine
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3
Q
What is Cancer?
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4
Q
Percent Distribution of Cancer
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5
Q
Cancer Death Rates
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6
Q
Cancer Rates/Trends
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7
Q
Cancer Treatment Types
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8
Q
Distribution of Cancer Sites
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9
Q
Erythropoetin and JAK-STAT Transduction
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10
Q
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11
Q
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Erythroid Hyperplasia in Bone Marrow
12
Q
A
13
Q
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14
Q
Normal Cells and Signaling Events
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15
Q
Serum and Cells that are starved from Serum
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16
Q
Cyclohexamide
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17
Q
Immediate Early Proteins and Delayed Early Genes
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18
Q
James Bond Model of Cancer
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19
Q
Oncogenes
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20
Q
Selected Oncogenes and Their Mode of Activation
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21
Q
Oncogenes and RAS
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22
Q
RAS and Cancer
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23
Q
Receptor that Activates RAS
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24
Q
Paracrine Growth Factors
A
25
Autocrine Growth Factors
26
Antibodies and Cancer Therapies
27
Herceptin
28
Blood Brain Barrier and Cancer
29
Steroid Hormones
30
RAS activation favors...
31
MYC and Cyclin D
32
Cyclin D
33
Retinoblastoma and Cancer
Which Cell Cycle is Effected?
34
Constitutive Activation
35
Mode of Activation of Selected Oncogenes
36
Result of Constitutive Activation
37
Constitutively Activated Receptors in Cancer
38
RAS and Point Mutations
39
RAS Point Mutations And Downstream Kinases
40
Effects of RAS Activation/Point Mutation
41
mTOR
42
Function of mTOR
43
Rapamycin Derative and Tumors
44
Complexity of mTOR Interactions
45
ABL
46
ABL Translocation
47
BCR ABL and Gleevec
48
Polycythemia
49
Jakafi
50
Proteosome
51
Cachexia and Inhibitors of Proteosomes
52
Velcade
53
Two Ways to Reduce Cell Cancer Growth
54
Getting Cancer Treatments into The Body
