Pharmacodynamics Pt. II Flashcards Preview

Fundamentals of Molecular Medicine > Pharmacodynamics Pt. II > Flashcards

Flashcards in Pharmacodynamics Pt. II Deck (24):
1

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Agonist vs. Anatgonist vs. Antagonist 10X

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Eqn for Agonist Alone

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Eqn for Agonist + Competitive Antagonist

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Competitive antagonist and the Schild Eqn

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Applying the Schlid Eqn

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Irreversible Antagonists

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Irreversible Antagonists with Spare Receptors

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Clinical Implications of Irreversible Antagonists

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Overdoses

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Reversible Competitive Antagonism

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Reversible vs. Irreversible Antagonists

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Spare Receptors and Physiological Response

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Response time vs. Absolute Sensitivity 

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Transmembrane signaling Mechanisms

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G-Protein Coupled Receptors

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Two Common Signaling Pathways

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Pharmacodynamics and regulating agonists and receptors

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Allosteric Modulation of Receptors

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Biased Agonists

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Receptor Subtypes

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Alpha 1 Receptor

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Beta 1 Receptors

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Beta II Receptors

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