Pharmacodynamics Pt. II Flashcards Preview

Fundamentals of Molecular Medicine > Pharmacodynamics Pt. II > Flashcards

Flashcards in Pharmacodynamics Pt. II Deck (24):
1

2

 

 

 

Agonist vs. Anatgonist vs. Antagonist 10X

3

 

 

 

Eqn for Agonist Alone

4

 

 


Eqn for Agonist + Competitive Antagonist

5

 

 

 

Competitive antagonist and the Schild Eqn

6

 

 

 

Applying the Schlid Eqn

7

 

 

 

Irreversible Antagonists

8

 

 


Irreversible Antagonists with Spare Receptors

9

 

 

 

Clinical Implications of Irreversible Antagonists

10

 

 

 

Overdoses

11

 

 

 

Reversible Competitive Antagonism

12

 

 

 

Reversible vs. Irreversible Antagonists

13

 

 

 

Spare Receptors and Physiological Response

14

 

 

 

Response time vs. Absolute Sensitivity 

15

 

 

 

Transmembrane signaling Mechanisms

16

 

 

 

G-Protein Coupled Receptors

17

 

 

 

Two Common Signaling Pathways

18

 

 

 

Pharmacodynamics and regulating agonists and receptors

19

 

 

 

Allosteric Modulation of Receptors

20

 

 

 

Biased Agonists

21

 

 

 

Receptor Subtypes

22

 

 

 

Alpha 1 Receptor

23

 

 

 

Beta 1 Receptors

24

 

 

 

Beta II Receptors

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