RBC’s don’t have...
RBC’s don’t have nuclei
What type of image is this?
Identify nm, c, n, and f
Compartmentalization of Nucleus
Compartmentalization of Nucleus allows us to control reactions in comparison to those in the cytoplasm.
Are there any organelles in the Nucleus?
No Organelles in the nucleus
Nucleolous is where...
Nucleolus = Where ribosomes are synthesized.
How Can we determine the location of proteins and whether or not they are inside or outside the nucleus?
What is the function and Structure of the Nuclear Lamina?
Describe the structure of what's in the image.
What are lamin associated diseases?
Mutations in different lamins lead to different disease.
Hutchinson Gifford Progeria Syndrome
HGPS — Premature aging
Describe the occurance in the electron micrograph.
Describe the Steps of the Nuclear Lamina in Mitosis
Identify relavent structure from the image.
Central Granual is a filler in the middle of the pore. Some pores have channels some have central granule.
Structure of the Nuclear Pore Complex
Function of the Nuclear Pore Complex
Nuclear Pore/Sieve Analogy
Nuclear Localization Sequence
Features of the NLS
NLS is essential and sufficient to allow proteins to be brought into the nucleus.
Describe the process of Nuclear Import
Describe the process of Nuclear Export
Nuclear Export Sequence
Classes of nuclear proteins that need to be exported
How does nuclear import and export work?
GTP hydrolysis in Nuclear Import
GTP Hydrolysis in Nuclear Export
Difference between GTP hydrolysis in export vs. import
Nuclear Export of mRNA
Describe the results and design of this experiment
Substances contained in the nucleus.
Are they membrane bound?
Additional Subnuclear Bodies