The Nucleus

Question 1

RBC’s don’t have…

Answer 1

RBC’s don’t have nuclei

Question 2

What type of image is this?

Identify nm, c, n, and f

Answer 2

Question 3

Compartmentalization of Nucleus

Answer 3

Compartmentalization of Nucleus allows us to control reactions in comparison to those in the cytoplasm.

Question 4

Are there any organelles in the Nucleus?

Answer 4

No Organelles in the nucleus

Question 5

Nucleolous is where…

Answer 5

Nucleolus = Where ribosomes are synthesized.

Question 6

Answer 6

Question 7

How Can we determine the location of proteins and whether or not they are inside or outside the nucleus?

Answer 7

Question 8

What is the function and Structure of the Nuclear Lamina?

Answer 8

Question 9

Describe the structure of what’s in the image.

Answer 9

Question 10

What are lamin associated diseases?

Answer 10

Mutations in different lamins lead to different disease.

Question 11

Hutchinson Gifford Progeria Syndrome

Answer 11

HGPS — Premature aging

Aging Phenotype

Question 12

Describe the occurance in the electron micrograph.

Answer 12

Question 13

Describe the Steps of the Nuclear Lamina in Mitosis

Answer 13

Question 14

Identify relavent structure from the image.

Answer 14

Question 15

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Question 16

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Question 17

Central Granual

Answer 17

Central Granual is a filler in the middle of the pore. Some pores have channels some have central granule.

Question 18

Structure of the Nuclear Pore Complex

Answer 18

Question 19

Function of the Nuclear Pore Complex

Answer 19

Question 20

Nuclear Pore/Sieve Analogy

Answer 20

Question 21

Nuclear Import

Answer 21

Question 22

Nuclear Localization Sequence

Answer 22

Question 23

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Question 24

Answer 24

Question 25

Features of the NLS

Answer 25

NLS is essential and sufficient to allow proteins to be brought into the nucleus.

Question 26

Describe the process of Nuclear Import

Answer 26

Question 27

Describe the process of Nuclear Export

Answer 27

Question 28

Nuclear Export Sequence

Answer 28

Question 29

Classes of nuclear proteins that need to be exported

Answer 29

Question 30

Answer 30

Question 31

How does nuclear import and export work?

Answer 31

Question 32

GTP hydrolysis in Nuclear Import

Answer 32

Question 33

GTP Hydrolysis in Nuclear Export

Answer 33

Question 34

Difference between GTP hydrolysis in export vs. import

Answer 34

Question 35

Nuclear Export of mRNA

Answer 35

Question 36

Describe the results and design of this experiment

Answer 36

Question 37

Substances contained in the nucleus. Are they membrane bound?

Answer 37

Question 38

Answer 38

Question 39

Nucleolous

Answer 39

Question 40

Additional Subnuclear Bodies

Answer 40