Autoimmune Hepatitis Flashcards
(9 cards)
What common symptom is associated with autoimmune hepatitis?
Amenorrhoea
Amenorrhoea is a common finding in patients with autoimmune hepatitis.
Which antibodies are typically raised in autoimmune hepatitis?
ANA, SMA, LKM1
These antibodies are indicative of autoimmune hepatitis and can aid in diagnosis.
What are the findings of a liver biopsy in autoimmune hepatitis?
Inflammation extending beyond limiting plate, ‘piecemeal necrosis’, bridging necrosis
These findings are characteristic of the liver damage seen in autoimmune hepatitis.
What is the primary management for autoimmune hepatitis?
Steroids, other immunosuppressants (e.g., azathioprine), liver transplantation
Management strategies may vary based on the severity of the disease.
What causes Type 1 autoimmune hepatitis?
Anti-nuclear antibodies (ANA) and/or anti-smooth muscle antibodies (SMA)
Type 1 autoimmune hepatitis can affect both adults and children.
Which type of autoimmune hepatitis affects children only?
Type 2 autoimmune hepatitis
Type 2 is characterized by the presence of anti-liver/kidney microsomal type 1 antibodies (LKM1).
What antibodies are associated with Type 2 autoimmune hepatitis?
Anti-liver/kidney microsomal type 1 antibodies (LKM1)
These antibodies are specific to Type 2 autoimmune hepatitis.
What is the characteristic antigen for Type 3 autoimmune hepatitis?
Soluble liver-kidney antigen
Type 3 autoimmune hepatitis primarily affects adults in middle age.
True or False: Autoimmune hepatitis can affect both adults and children.
True
Type 1 affects both groups, while Type 2 affects children only.
