Obesity Flashcards
(19 cards)
What is Class I obesity?
BMI of 30-34.9
What is Class II obesity?
35-39.9
What is Class III obesity?
Over 40 BMI
When can pharmacotherapy be considered for obesity?
Individuals who cannot achieve weight loss goals through lifestyle alone
When is GLP-1 analogues indicated?
individuals with a BMI ≥35, or ≥30 with weight-related comorbidities such as type 2 diabetes or hypertension
-> should be an addition to diet and exercise
When should liraglutide be discontinued for treatment in obesity?
Treatment should be discontinued after 12 weeks if the person has not lost at least 5% of their initial body weight
When is bariatri surgery indicated?
Recommended for individuals with severe obesity (BMI ≥ 40) or those with a BMI ≥ 35 with significant obesity-related comorbidities.
What is the first step in the management of obesity?
Conservative: diet, exercise
The management of obesity consists of a step-wise approach.
What are the three main approaches to managing obesity?
- Conservative
- Medical
- Surgical
What is Orlistat and how does it function?
A pancreatic lipase inhibitor used in the management of obesity.
What are the adverse effects of Orlistat?
- Faecal urgency/incontinence
- Flatulence
What is the lower dose version of Orlistat that is available without prescription?
‘Alli’
What are the NICE criteria for prescribing Orlistat?
- BMI of 28 kg/m² or more with associated risk factors
- BMI of 30 kg/m² or more
- Continued weight loss of 5% at 3 months
For how long is Orlistat normally used?
< 1 year
What is Liraglutide and what is its primary use?
A glucagon-like peptide-1 (GLP-1) mimetic used in the management of type 2 diabetes mellitus (T2DM).
How is Liraglutide administered?
Once daily subcutaneous injection
What effect does Liraglutide have when used in the management of T2DM?
Causes weight loss in a significant proportion of patients.
What are the current NICE criteria for the use of Liraglutide?
- BMI of at least 35 kg/m²
- Prediabetic hyperglycaemia (e.g. HbA1c 42 - 47 mmol/mol)
