PPT Mental Health Flashcards
(231 cards)
What is a risk associated with SSRIs?
Serotonin syndrome, increased risk of bleeding, acute urinary retention
SSRIs can lead to serious side effects that need monitoring.
What is the initial management strategy for aggressive behavior?
Restrictive interventions followed by observation
If aggressive behavior continues, rapid tranquilisation with benzodiazepines may be necessary.
How often should monitoring occur during rapid tranquilisation?
Every 15 minutes
Continuous monitoring is essential to ensure patient safety.
What is the preferred medication for rapid tranquilisation if there is an uncertain antipsychotic drug history?
IM lorazepam
Lorazepam is chosen for its safety profile in these situations.
What alternative medications can be used for rapid tranquilisation?
IM haloperidol and promethazine
ECG monitoring is required due to the risk of cardiac arrhythmia.
Which areas of the brain are involved in dependence mechanisms for different substances?
Ventral regimental area for amphetamines, cocaine, opioids; nucleus accumbens for alcohol, cannabinoids
These areas are critical in understanding addiction mechanisms.
Who should be admitted for acute alcohol withdrawal?
Young person under 16, vulnerable person with co-morbidities, learning disability, high risk of withdrawal
Admission is crucial for those at significant risk.
What daily alcohol consumption level is at greatest risk for delirium tremens?
30 units of alcohol a day
This level indicates a high risk for severe withdrawal symptoms.
What vitamin supplementation is recommended for high-risk patients in alcohol withdrawal?
Pabrinex IV
Pabrinex contains thiamine and other vitamins essential for recovery.
What is given to low-risk patients for vitamin supplementation during alcohol withdrawal?
Thiamine
Thiamine is crucial to prevent Wernicke’s encephalopathy.
What medication is recommended for diarrhoea in alcohol withdrawal?
Loperamide
Loperamide helps manage gastrointestinal symptoms.
Which benzodiazepine has the highest potency?
Chlordiazepoxide
It is metabolised by CYP3A4 but has the slowest action and longest half-life.
Which benzodiazepine has the fastest action and is metabolised by CYP2C9?
Diazepam
It has a prolonged half-life in patients with renal or hepatic impairment.
What is the lowest potency benzodiazepine?
Lorazepam
Lorazepam has no active metabolite and undergoes non-CYP glucuronidation in the liver.
What is Naltrexone used for?
It is an opioid antagonist best for highly motivated people who wish to remain abstinent
Naltrexone helps reduce cravings and supports recovery.
What is Methadone used for?
It is a long-acting opioid agonist that reduces euphoric effects and treats withdrawal symptoms over 24 hours
Methadone is administered as a single daily dose.
What is Buprenorphine?
A partial mu opioid agonist for long-term treatment as a daily sublingual dose
It has a reduced initial risk of fatal overdose.
What is the purpose of Flumazenil?
To reverse benzodiazepine overdose
It works by competitively inhibiting benzodiazepine receptor recognition.
What is Fomepizol used for?
To reverse alcohol overdose
It acts as a competitive inhibitor of alcohol dehydrogenase.
What is sodium bicarbonate used to treat?
Tricyclic antidepressant poisoning
It increases extracellular sodium and serum pH to counteract toxicity.
What forms does nicotine replacement therapy take?
Patches and gums
It is safe for pregnancy and has no cancer risk.
What is Bupropion?
A dopamine and noradrenaline reuptake inhibitor
It should be taken while smoking and stopped 2 weeks after.
What is the function of Varenicline?
Partial agonist at nicotine receptors
It is currently not available for smoking cessation.
List the SSRIs.
- Citalopram
- Fluoxetine
- Paroxetine
- Sertraline
SSRIs are commonly prescribed for depression.