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Year 3 > PPT laxatives, Anti Diarrhoea And PPI > Flashcards

PPT laxatives, Anti Diarrhoea And PPI Flashcards

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1
Q

What is Pantoprazole classified as?

A

A PPI with a longer duration of action

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2
Q

What should be held during variceal bleeding?

A

Antihypertensives

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3
Q

What do NSAIDs reduce the production of?

A

Prostaglandins that protect the stomach lining

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4
Q

What constitutes triple therapy for Peptic ulcer disease?

A
  • PPI like lansoprazole
  • Amoxicillin
  • EITHER Metronidazole OR Clarithromycin
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5
Q

What is the alternative triple therapy for patients with penicillin allergy?

A

PPI, with clarithromycin AND metronidazole

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6
Q

What is included in quadruple therapy if triple therapy is ineffective?

A
  • Bismuth
  • PPI
  • Tetracycline
  • Metronidazole
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7
Q

What should be added if quadruple therapy is ineffective?

A

Metronidazole and Leo flora

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8
Q

What is an alternative to bismuth?

A

Tripotassium dicitratobismuthate

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9
Q

What do bulk forming laxatives like Ispaghula husk do?

A

Increase the weight and water content of stool by adding insoluble fibre

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10
Q

What is Ispaghula husk also known as?

A

Fybogel

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11
Q

What do osmotic laxatives do?

A

Increase the water content of stools

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12
Q

What are examples of osmotic laxatives?

A
  • Polyethylene glycol
  • Lactulose
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13
Q

What are examples of irritant stimulant laxatives?

A
  • Bisacodyl
  • Senna
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14
Q

How does Senna function in the body?

A

Stimulates the enteric nerves for peristalsis and mobility

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15
Q

What are faecal softeners?

A
  • Docusate sodium
  • Co-danthrusate
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16
Q

What is the first-line treatment for drug-induced constipation?

A

Stimulant adaptive

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17
Q

What should be avoided in drug-induced constipation?

A

Bulk forming laxatives

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18
Q

What is the first-line treatment for chronic constipation?

A

Bulk forming laxative with lots of fluid

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19
Q

What is the second-line treatment for chronic constipation?

A

Stool softener

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20
Q

What is the fourth-line treatment for chronic constipation?

A

Osmotic laxative

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21
Q

What is the first-line treatment for chronic constipation with IBS?

A

Antispasmodics and increasing soluble fibre

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22
Q

What is Linaclotide used for?

A

As a last resort in constipation with IBS

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23
Q

What is the first-line treatment for chronic constipation with low mobility?

A

Stool softener

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24
Q

What is the first-line treatment for chronic constipation during pregnancy?

Study These Flashcards
A

Bulk forming laxative

25
Which laxatives are considered safe during pregnancy?
* Senna * Magnesium salts * Lactulose * Docusate laxatives
26
What is suitable for the elderly with constipation?
Co-dantrhamer and co-danthrusate
27
What can be used for opioid-induced constipation when other laxatives are ineffective?
Peripheral opioid receptor antagonist methylnaltrexone
28
What should be used for neurological disease affecting bowel motility?
Faecal softener with regular enemas or rectal washouts
29
What is Lactulose useful for?
Hepatic encephalopathy
30
What is Pantoprazole classified as?
A PPI with a longer duration of action
31
What should be held during variceal bleeding?
Antihypertensives
32
What do NSAIDs reduce the production of?
Prostaglandins that protect the stomach lining
33
What constitutes triple therapy for Peptic ulcer disease?
* PPI like lansoprazole * Amoxicillin * EITHER Metronidazole OR Clarithromycin
34
What is the alternative triple therapy for patients with penicillin allergy?
PPI, with clarithromycin AND metronidazole
35
What is included in quadruple therapy if triple therapy is ineffective?
* Bismuth * PPI * Tetracycline * Metronidazole
36
What should be added if quadruple therapy is ineffective?
Metronidazole and Leo flora
37
What is an alternative to bismuth?
Tripotassium dicitratobismuthate
38
What do bulk forming laxatives like Ispaghula husk do?
Increase the weight and water content of stool by adding insoluble fibre
39
What is Ispaghula husk also known as?
Fybogel
40
What do osmotic laxatives do?
Increase the water content of stools
41
What are examples of osmotic laxatives?
* Polyethylene glycol * Lactulose
42
What are examples of irritant stimulant laxatives?
* Bisacodyl * Senna
43
How does Senna function in the body?
Stimulates the enteric nerves for peristalsis and mobility
44
What are faecal softeners?
* Docusate sodium * Co-danthrusate
45
What is the first-line treatment for drug-induced constipation?
Stimulant adaptive
46
What should be avoided in drug-induced constipation?
Bulk forming laxatives
47
What is the first-line treatment for chronic constipation?
Bulk forming laxative with lots of fluid
48
What is the second-line treatment for chronic constipation?
Stool softener
49
What is the fourth-line treatment for chronic constipation?
Osmotic laxative
50
What is the first-line treatment for chronic constipation with IBS?
Antispasmodics and increasing soluble fibre
51
What is Linaclotide used for?
As a last resort in constipation with IBS
52
What is the first-line treatment for chronic constipation with low mobility?
Stool softener
53
What is the first-line treatment for chronic constipation during pregnancy?
Bulk forming laxative
54
Which laxatives are considered safe during pregnancy?
* Senna * Magnesium salts * Lactulose * Docusate laxatives
55
What is suitable for the elderly with constipation?
Co-dantrhamer and co-danthrusate
56
What can be used for opioid-induced constipation when other laxatives are ineffective?
Peripheral opioid receptor antagonist methylnaltrexone
57
What should be used for neurological disease affecting bowel motility?
Faecal softener with regular enemas or rectal washouts
58
What is Lactulose useful for?
Hepatic encephalopathy

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