COPD Flashcards

(56 cards)

1
Q

What does the rescue pack for COPD contain?

A

Amoxicillin
Corticosteroid like prednisolone

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2
Q

What is given for prophylaxis fo COPD exacerbation?

A

For exacerbations of 4 or more in a year, azithromycin is given 3 x a week

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3
Q

What is Grade 1 COPD?

A

Over 80%

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4
Q

What is Grade 2 COPD?

A

50-79%

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5
Q

What is Grade 3 COPD?

A

30-49%

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6
Q

What is Grade V COPD?

A

Less than 30%

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7
Q

Which investigations to perform for COPD?

A

Spirometry: FEV1/FVC ratio should be less than 0.7
Sputum culture
FBC for polycythaemia fromc chronic hypoxaemia or anaemia of chronic disease
ECG findings correlating with RHF
CXR

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8
Q

What are the CXR findings?

A

Flattening of diaphragm
Bullae

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9
Q

What is first line for patients who are limited by breathlessness?

A

SABA or SAMA

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10
Q

What is given for patients with features of asthma and steroid responsiveness?

A

LABA and ICS

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11
Q

What is third line?

A

LABA + LAMA + ICS

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12
Q

What can be given additionally if not stabilised with 3rd line therapy and asthma features/steroid responsive?

A

Oral steroid
Oral theophylline
Oral phosphodiesterase-4 inhibitor like roflumilast

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13
Q

What is given for a COPD patient with significant symptoms but no exacerbation?

A

LAMA or LABA
-> if symptoms persist, escalate to dual therapy

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14
Q

What is given for patients with 2 exacerbations OR 1 hospitalisation?

A

LAMA is first line unless asthmatic features then LABA + ICS

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15
Q

What is given for patients with 2 exacerbations OR 1 hospitalisation and LAMA is ineffective?

A

Dual therapy

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16
Q

What is the surgical managmeent for COPD?

A

Lung volume reduction

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17
Q

Which patients should be referred for LTOT?

A

Oxygen saturations <92% in air or cyanosis
FEV1 <30% predicted (consider referring if <49%)
Polycythaemia
Peripheral oedema or raised jugular venous pressure (suggesting cor pulmonale)

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18
Q

What should the ABG values be for LTOT?

A

PaO2 below 7.3kPa
PaO2 7.3-8kPa with any of secondary polycythaemia, peripheral oedema or pulmonary hypertension

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19
Q

When is non-invasive ventilation given?

A

I level positive airway pressure for uncompensated Type 2 respiratory failure, where CO2 is more than 6 and PaO2 is less than 8

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20
Q
A
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21
Q

How to determine between infective exacerbation and infection?

A

CXR findings will show pacification for infection
There will be an absence of a wheeze

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22
Q

When is non-invasive ventilation used in COPD?

A

Hypercapnic respiratory failure for respiratory acidosis

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23
Q

When should non-invasive ventilation be avoided?

A

When patients lose their hypoxia respiratory drive due to overoxygenation

24
Q

How is overoxygenation of patients in COPD present?

A

Reduced work of breathing, looking a calmer from CO2 narcosis with hypoxia but oxygen saturation of 93% or higher. Therefore they should be switched onto a lower oxygen mask to achieve a target saturation of 88-92%.

25
26
What to do if a COPD patient is hypoxic and ABG is not available?
Provide high flow oxygen due to risk of type 2 respiratory failure
27
Which investigation is sued to confirm COPD?
Spirometry
28
When is PEFR used as an investigation?a
Asthma
29
What is considered an asthmatic feature?
Atopic dermatitis
30
How does high oxygen worsen hypercapnic ventilation?
V/Q mismatch - chronic lung damage from COPD causes the lungs to compensate by vasoconstricting the blood vessels in these areas and vasodilating the ones in the healthy areas. Excess oxygen causes vasodilation of the blood vessels throughout the lungs, increasing the amount of blood going to the damaged alveoli and impairing effective gas exchange. The Haldane effect - at higher concentrations of oxygen, more carbon dioxide is released from haemoglobin into the circulation.(resulting in hypercapnia).
31
What is the indication for LTOT?
The criteria defined for offering LTOT to patients with COPD are: pO2 <7.3 kPa OR pO2 7.3 - 8 kPa AND one of the following: secondary polycythaemia, peripheral oedema, or pulmonary hypertension
32
What is the oxygen flow for 24% Venturi mask in COPD?
2-4 L
33
What inital oxygen therapy for patients with type 2 resp failure in COPD?
4L of oxygen via Venturi mask at 24-28%, aiming for target sat of 88-92% Bronchdoiator therapy Steroids
34
What should be given if patient fails to respond to ventricular mask oxygen?
Over 1 hour and they remain in respiratory fialure, give non-invasive ventilation Steroids
35
What is the V/Q mismatch in COPD?
Low due to decreased ventilation but higher perfusion because of greater cardiac output
36
How to differentiate between acute and chronic respiratory acodiosis?
High bicarbonate levels in chronic because of chronic compensation
37
ECG findings for COPD?
Right axis deviation Prominent p waves in inferior leads Inverted P waves in lateral dead’s Delayed R/S transition Multi focal atrial tachycardia
38
What increases survival in COPD?S
Smoking cessation Long term oxygen therapy
39
What are the asthmatic features? d
Diurnal variation worse at. Night and early morning Eczema
40
What is the oxygen flow in 28% Venturi mask inCOPD?
4L/min
41
What is used to grade COPD severity?
GOLD criteria: GOLD A 0–1 exacerbations per year + fewer symptoms GOLD B 0–1 exacerbations per year + more symptoms GOLD C 2 or more exacerbations per year + fewer symptoms GOLD D 2 or more exacerbations per year + more symptoms
42
What is the criteria for COPD admission?
severe breathlessness acute confusion or impaired consciousness cyanosis oxygen saturation less than 90% on pulse oximetry. social reasons e.g. inability to cope at home (or living alone) significant comorbidity (such as cardiac disease or insulin-dependent diabetes)
43
Which virus causes COPD exacerbation?
Human rhinovirus
44
Which bacteria causes COPD exacerbation other than haemophilus influenza?
Streptococcus pneumoniae Moraxella catarrhalis
45
What is given for COPD exacerbation?
increase the frequency of bronchodilator use and consider giving via a nebuliser give prednisolone 30 mg daily for 5 days
46
When to give antibiotics for COPD exacerbation?
If sputum is purulent or clinical signs of pneumonia
47
What is the first line drugs for COPD exacerbation?
the BNF recommends one of the following oral antibiotics first-line: amoxicillin or clarithromycin or doxycycline.
48
What is the criteria for using non-invasive ventilation?
typically used for COPD with respiratory acidosis pH 7.25-7.35 NIV can be used in patients who are more acidotic (i.e. pH < 7.25) but that a greater degree of monitoring is required (e.g. HDU) and a lower threshold for intubation and ventilation should be
49
What is the level of BiPAP usedf or expiratory
4-5cm H20 for expiratory
50
What is the level of BiPAP used for Inspiratory?
12-15cm H20
51
Which materials can cause COPD?
Coal Cotton Cement Grain
52
What should be done before prescribing azithromycin?
LFTs and ECG to exclude QT prolongation due to risk
53
What is reccomended for cor pulmonale?
Loop diuretics -> not any other medications
54
What is an indicator for lung reduction surgery?
Predominant upper lobe emphysema FEV1>20% predicted, PaCO2 <7 and Transfer capacity of the lung for carbon monoxide (TlCO) >20%.
55
What does signet ring indicate on CT?
Bronchieactasis sats the bronchus is dilated
56
What reduces exacerbations of Bronchieactasis?
Postural drainage, a type of chest physiotherapy done twice a day