9.21 Injury, Inflammation, Healing 6 Flashcards Preview

8501 Clin Med > 9.21 Injury, Inflammation, Healing 6 > Flashcards

Flashcards in 9.21 Injury, Inflammation, Healing 6 Deck (22)
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1

What is the general term for WBCs?

leukocytes

2

What is the pneumonic for the types of leukocytes?

Never
Let
Monkeys
Eat
Bananas

3

What does Never Let Monkeys Eat Bananas stand for?

(types of leukocytes)

- Neutrophils
- Lymphocytes
- Monocytes
- Eosinophils
- Basophils

4

What are neutrophils?

the predominant phagocytes in the early inflammatory process

5

When do neutrophils arrive on the scene?

6-12 hours after initial injury

**first on the job**

6

neutrophils and cell division/lifespan

- incapable of cell division
- short lived

7

What happens to neutrophils when they die?

- become part of exudate/pus
- removed from body

8

What are the primary roles of neutrophils?

- remove debris and dead cells from sterile lesions
- phagocytosis of bacteria in nonsterile lesions

9

What do lymphocytes mature into?

- T cells
- B cells
- plasma cells

10

Lymphocytes are important in _____

immunity

11

Concentrations of lymphocytes

Won't see in large concentrations unless there's something like leukemia going on

12

Which are the largest of the normal blood cells?

monocytes

13

Monocytes are produced here

bone marrow

14

After entry into the _______, monocytes enter _______ to develop into ________

- inflammatory site
- circulation
- macrophages

15

Monocytes replace _______ 24 hours after injury

neutrophils

16

Monocytes are useful for this

long term defense

17

Monocytes are seen in higher proportions in ___________

chronic inflammation

18

Body's primary defense against parasites

eosinophils

19

How do eosinophils act?

- mildly phagocytic
- help regulate vascular mediators released by mast cels
- helps to limit inflammation

20

What are basophils?

- mobile mast cells
- release similar inflammatory agent to eosinophils (?)

21

Characteristics of chronic inflammation

- dense infiltration of lymphocytes and macrophages
- granuloma formation
- epithelioid cell formation
- giant cell formation

22

Components of the inflammatory rxn

- vascular alterations
- leukocyte accumulations
- chemical mediation of inflammation
- phagocytosis

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