Viruses/Fungi 7 Flashcards Preview

8501 Clin Med > Viruses/Fungi 7 > Flashcards

Flashcards in Viruses/Fungi 7 Deck (22):
1

How many fungi can cause human infection?

over 200 species

2

fungi are most problematic in these pts

immunocompromised

3

systemic antifungal agents are used for

tx of deep (invasive) infections

- Candida
- Cryptococcus

4

IV systemic antifungal agent

Amphotericin B (Amphocin, Fungizone)

5

These are better tolerated, but may not be as effective as amphotericin B

Fluconazole (Diflucan)

6

Diflucan administration

IV or oral

7

side effects of amphotericin B

- HA
- joint and muscle pain
- fever
- weakness
- GI upset

8

side effects of Diflucan

- hepatotoxic
- severe skin rxns (S-J syndrome)
- HA
- GI upset

9

When would a local antifungal be chosen?

when antifungals are too toxic to be administered systemically

10

Lamisil used for these

- tinea pedis
- tinea cruris
- ringworm

11

-azole antifungals used for

Candida infections (skin/membranes)

12

local antifungal agents: side effects

- mild
- usually local

13

Malaria historically treated with this since the 17th century

quinine

14

Malaria now treated withy derivatives of this

chloroquine

15

adverse effects of antiprotozoal drugs

- vary
- GI
- HA

16

most common protozoan infectious agent

Toxoplasma gondii

17

Toxoplasma gondii found here

- many animals and birds
- reproduces in cats
- found in cat feces

18

toxoplasmosis

- flu-like symptoms
- parasites are walled off in cysts in the affected organs

19

What is a helminth?

parasitic worm

20

Examples of helminths

- tapeworms
- roundworms
- flukes

21

helminth route of infection

- ingestion of eggs in contaminated food and water
- eggs hatch
- adult worm lodge in tissue
- steal nutrients from host

22

Which drugs are used for helminthes?

-azoles

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