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Flashcards in Hematologic Disorders 5 Deck (20)
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1

Patient blood management develops an individualized plan for each person to minimize the need for transfusion

3 principles

- manage anemia
- minimize blood loss
- optimize hemostasis

2

Why does pt blood management need to be developed to minimize the need for transfusion?

- Techniques acceptable for religious groups (Jehovah’s Witnesses)
- New infectious agents possible
- Risks associated with transfusions

3

What needs to be done for pts who have had transfusions in the acute care, surgical, and post-op settings? (PT)

- Monitor lab values when treating patients
- Adjust treatment and intensity accordingly

4

disorders of iron absorption =

hemochromatosis

5

What type of disorder is hemochromatosis?

autosomal recessive hereditary disorder

6

What causes hemochromatosis?

mutations in genes of any of the proteins that regulate the entry of iron into th eblood

7

hemochromatosis severity depends upon:

variable, but thought to have an environmental component
- alcohol intake
- coexistence of Hep B/C

8

What does hemochromatosis result in (liver + iron)

Excessive absorption of iron from small intestine

9

hemochromatosis: sx onset

- present at birth
- onset of sx usually between 40-60 y.o.

10

hemochromatosis: prevalence

- Equal between men and women
- Men experience sx 5-10x more often than women

11

What are some of the sx associated with hemochromatosis?

- weakness
- chronic fatigue
- myalgia
- joint pain
- abnormal bronzing of the skin

12

What is used to diagnose hemochromatosis?

- blood tests
- liver biopsy

13

Medical tx for hemochromatosis (therapeutic phlebotomy)

Therapeutic phlebotomy until iron stores are at normal level

14

initial tx for hemochromatosis (amts)

- may be 1 pint
- 1-2x per week

15

maintenance therapy for hemochromatosis (amts)

- 1 pint
- every 2-4 months for life

16

What can hemochromatosis lead to if left untreated?

- hepatomegaly
- pancreatic damage
- DM
- destructive arthritis
- liver failure
- cardiac myopathy
- CHF
- arrhythmias
- impotence in men
- decreased libido and sterility in women

17

What is a major indicator with a pt who has hemochromatosis that distinguishes is from OA?

pt may report twinges of pain when flexing small joints of hands

ARTHROPATHY

18

Arthropathy is present in ______% of cases of hemochromatosis

40-60%

19

joint destruction with hemochromatosis

likely irreversible

20

For pts who have hemochromatosis, what do PT interventions seek to address?

- flexibility
- strength
- assistive devices
- orthoses
- fall prevention

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