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Flashcards in MS 1 Deck (19)
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1

MS is the most common _____________

inflammatory demyelinating disease of the CNS

2

What nerves does MS spare?

peripheral

3

Inflammatory/demyelinating lesions form these

scars/plaques

4

Where are demyelinating scars/plaques from MS found?

CNS white matter

5

MS is characterized by these phases

- exacerbations
- remissions

6

When do s/s of MS begin occurring?

- between 20-40
- peak at age 30

7

Rare onset of MS occurs when?

- childhood
- after 50

8

Women/Men are 2x as likely to get MS

Women

9

What increases the likelihood of MS 10-fold?

family hx

10

Is there an environmental component to MS?

yes - more prevalent in colder climates

11

What are the types of MS?

- Clinically isolated syndrome (CIS)
- Relapsing-Remitting (RRMS)
- Primary Progressive (PPMS)
- Secondary Progressive (SPMS)

12

What is CIS?

- FIRST episode of neuro sx due to demyelination of CNS
- MUST last at least 24 hours

13

How is CIS different from MS?

Characteristic of MS but does not yet meet criteria for dx

14

What must happen for it to be categorized as MS?

MUST have 2 separate documented lesions or episodes

15

What is the most common type of MS?

Relapsing-Remitting (RRMS)

16

What percentage of pts have RRMS?

85%

17

What is RRMS?

- Periods of clearly defined exacerbations followed by period of remission
- Function returns to baseline/near baseline

18

What is Primary Progressive MS?

Worsening function from onset of sx

19

What is secondary progressive MS?

Follows an initial RRMS course

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