Autoimmune Disorders: PMR Flashcards Preview

8501 Clin Med > Autoimmune Disorders: PMR > Flashcards

Flashcards in Autoimmune Disorders: PMR Deck (18):
1

What is PMR? (general)

A systemic, rheumatic inflammatory disorder with an unknown cause

2

Age groups that are affected by PMR?

- almost exclusive to people > 55
- 10x more prevalent in people over 80

3

(Men/Women) get PMR more often

women

4

Which race gets PMR most often?

white people

5

Primary complaint with PMR

severe MUSCLE aching and stiffness

(as compared to joints)

6

PMR is closely linked to this comorbidity

GCA = giant cell (temporal) arteritis

7

Which arteries are affected with GCA?

medium sized arteries (carotid)

8

Which branches of the carotid arteries are most often affected by GCA?

- cranial branch
- extra-cranial branch

9

Why is GCA associated with headaches?

associated with optic nerve

10

What are the most common symptoms with GCA?

severe, unilateral or bilateral HA

11

What are the clinical s/s of PMR?

- muscle pain
- stiffness after rest
- weakness, fatigue, malaise
- low grade fever
- sweats
- HA
- weight loss
- depression
- vision changes

12

What often leads to misdiagnosis of PMR?

orocranial symptoms

13

What is a medical dx of PMR made based on?

- age
- clinical presentation
- very high ESR

14

ESR =

Erythrocyte
Sedimentation
Rate

15

What does the ESR tell you?

- how quickly RBC settle in a test tube in 1 hr
- nonspecific test for inflammation

16

What are the treatment options for PMR?

- oral corticosteroids
- otherwise, symptoms are self-limiting

17

When would corticosteroids be used for PMR? What is their effect?

- for longer lasting disease course
- relieves symptoms quickly but does not cure

18

Self-limiting symptoms for PMR: time frame

last 2-3 years

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