Flashcards in Ciccone Doc for Pharm Deck (13)
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1
selective toxicity
- kills or attenuates pathogen growth
- no excessive damage to host
2
Bacteria are structurally capable of independent life, but need this
nourishing host
3
Broad spectrum antibacterial agents
- kill everything
- no specificity
4
What does the lack of specificity of broad spectrum antibacterial agents lead to?
- less effective later on
- some bacteria will already have a tolerance built up
5
bactericidal
- is bacteriostatic
- limits growth and proliferation
6
Why is it common to see N/V with antibiotics?
they're cleaning out intestinal flora
7
When can drug resistance occur? What does this mean?
- can occur with overprescription of antibiotics
- must be mindful of prescribing so that it won't have such a huge impact
8
Basic mechanisms of action: Where do antibacterial agents differ?
location at which they impact the bacteria
9
Where might antibacterial agents act?
- cell membrane synthesis
- cell wall synthesis
- inhibit protein synthesis
- inhibit DNA/RNA synthesis
10
What are the drugs that act on cell membrane synthesis?
- Penicillins
- Cephalosporins
- Carbapenems
11
What are the drugs that act on cell wall synthesis?
- Topical (i.e. bacitracin)
- Vancomycin
12
What are the drugs that act on protein synthesis?
- Erythromycin
- Tetracycline
- Chloromycetin
- Clindamycin
- Ketek
13