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8501 Clin Med > Ciccone Doc for Pharm > Flashcards

Flashcards in Ciccone Doc for Pharm Deck (13)
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1

selective toxicity

- kills or attenuates pathogen growth
- no excessive damage to host

2

Bacteria are structurally capable of independent life, but need this

nourishing host

3

Broad spectrum antibacterial agents

- kill everything
- no specificity

4

What does the lack of specificity of broad spectrum antibacterial agents lead to?

- less effective later on
- some bacteria will already have a tolerance built up

5

bactericidal

- is bacteriostatic
- limits growth and proliferation

6

Why is it common to see N/V with antibiotics?

they're cleaning out intestinal flora

7

When can drug resistance occur? What does this mean?

- can occur with overprescription of antibiotics
- must be mindful of prescribing so that it won't have such a huge impact

8

Basic mechanisms of action: Where do antibacterial agents differ?

location at which they impact the bacteria

9

Where might antibacterial agents act?

- cell membrane synthesis
- cell wall synthesis
- inhibit protein synthesis
- inhibit DNA/RNA synthesis

10

What are the drugs that act on cell membrane synthesis?

- Penicillins
- Cephalosporins
- Carbapenems

11

What are the drugs that act on cell wall synthesis?

- Topical (i.e. bacitracin)
- Vancomycin

12

What are the drugs that act on protein synthesis?

- Erythromycin
- Tetracycline
- Chloromycetin
- Clindamycin
- Ketek

13

What are the drugs that act on DNA/RNA synthesis?

- Fluoroquinolones
- Sulfanomides

Decks in 8501 Clin Med Class (102):