Flashcards in Ciccone Doc 2 Deck (16):
1
Act on membrane synthesis
- penicillins
- cephalosporins
- carbapenems
2
Side effects of penicillins
skin rxns
3
What are the skin rxns that can happen from penicillins?
- Stephens-Johnson syndrome
- Toxic epidermal necrolysis
4
Toxic epidermal necrolysis is (non-life threatening/life threatening)
life threatening
5
Stephens-Johnson syndrome
painful rash followed by blisters
6
Prolonged use of penicillins can cause
CNS issues
7
CNS issues from penicillin long term use
- hallucinations
- confusion
- hemolytic anemia
- thrombocytopenia
8
Penicillins have cross-sensitivity with
cephalosporins
9
Cephalosporins work on the same bugs as
penicillins
10
These are better for UTIs than penicillins
cephalosporins
11
Cephalosporins are used _______, often seen with _____ patients
- prophylactically
- SCI
12
These antibiotics that work on membrane synthesis can cause CNS abnormalities
carbapenems
13
Who is vulnerable to CNS abnormalities caused by carbapenems?
- pre-existing seizure disorder
- drug dosage too high
14
Example of a topical drug that acts on cell wall synthesis
Bacitracin
15
Side effect of Bacitracin
local hypersensitivity
16