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8501 Clin Med > Ciccone Doc 2 > Flashcards

Flashcards in Ciccone Doc 2 Deck (16):
1

Act on membrane synthesis

- penicillins
- cephalosporins
- carbapenems

2

Side effects of penicillins

skin rxns

3

What are the skin rxns that can happen from penicillins?

- Stephens-Johnson syndrome
- Toxic epidermal necrolysis

4

Toxic epidermal necrolysis is (non-life threatening/life threatening)

life threatening

5

Stephens-Johnson syndrome

painful rash followed by blisters

6

Prolonged use of penicillins can cause

CNS issues

7

CNS issues from penicillin long term use

- hallucinations
- confusion
- hemolytic anemia
- thrombocytopenia

8

Penicillins have cross-sensitivity with

cephalosporins

9

Cephalosporins work on the same bugs as

penicillins

10

These are better for UTIs than penicillins

cephalosporins

11

Cephalosporins are used _______, often seen with _____ patients

- prophylactically
- SCI

12

These antibiotics that work on membrane synthesis can cause CNS abnormalities

carbapenems

13

Who is vulnerable to CNS abnormalities caused by carbapenems?

- pre-existing seizure disorder
- drug dosage too high

14

Example of a topical drug that acts on cell wall synthesis

Bacitracin

15

Side effect of Bacitracin

local hypersensitivity

16

Side effects of Vancomycin

- bitter taste in mouth
- nephrotoxicity
- ototoxicity
- red man rash from vancomycin load
- hypersensitivity

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