9.21 Injury, Inflammation, Healing 5 Flashcards Preview

8501 Clin Med > 9.21 Injury, Inflammation, Healing 5 > Flashcards

Flashcards in 9.21 Injury, Inflammation, Healing 5 Deck (20)
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1

local factors affecting the healing process

- type, size, location of injury
- infection
- vascular supply
- external forces
- movement

2

First local factor affecting the healing process that you should look at

vascular supply

3

How might modalities play a role in the healing process?

External force: Is it contributing to or detracting from the healing process?

4

Systemic factors affecting the healing process

- age
- disease
- meds
- nutrition

5

What happens during hemostasis and degeneration?

- coagulation to stop bleeding
- formation of hematoma
- necrosis of dead cells
- beginning to repair tissue defect

6

function of inflammation

- protective
- curative

7

When does inflammation begin?

when the blood clot forms

8

When does the proliferation and migration phase begin?

within 2 days of injury

9

What happens in the proliferation/migration phase?

endothelial cells proliferate and migrate to cover and vascularize the wound

10

What happens to scar tissue during the remodeling and maturation phase?

reduced and remodeled, possibly over many months

11

Platelets bind to _____ and release _____

- collagen
- fibrin

12

What do fibrin and fibronectin limit?

- fluid drainage
- hemorrhaging

13

How do fibrin and fibronectin make sure cells have something to grow onto?

by laying a "net" over the sound

14

How do fibrin and fibronectin help with clot formation?

by giving the platelets something to hang onto

15

The hemostatic response is also an important component of this response

inflammatory

16

When does acute inflammation subside?

once the injurious agent is removed

17

Acute inflammation follows this

an injury

18

Chronic inflammation is the result of

- extensive necrosis OR
- inability of parenchymal cells to regenerate

19

This is needed for clotting

prothrombin

20

What is globulin part of?

immune system

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