Viruses/Fungi 3 Flashcards

(35 cards)

1
Q

HSV-1: incidence

A

~70% over 12 harbor HSV-1

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2
Q

HSV-1 is responsible for

A

cold sores

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3
Q

How can HSV be transmitted to genitals?

A

oral sex

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4
Q

local s/s of HSV-1:

A

vesicles and ulcers on:

  • mouth
  • throat
  • lips
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5
Q

possible ystemic s/s of HSV-1:

A
  • fever
  • myalgias
  • malaise
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6
Q

timeframe for sx resolution of HSV-1:

A

3-14 days

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7
Q

recurrence of HSV-1

A

usually milder

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8
Q

HSV-2 is responsible for:

A
  • genital ulcers

- genital herpes

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9
Q

How many people have HSV-2?

A

more than 50 million

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10
Q

HSV-2 and HIV

A

HSV-2 increases the risk of acquiring HIV at least 2x!

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11
Q

s/s of HSV-2: vesicles and lesions on cutaneous surfaces of:

A
  • genitals
  • cervix
  • buttocks
  • bladder
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12
Q

lesion characteristics: HSV-2

A
  • painful
  • small
  • grouped
  • burning
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13
Q

timeframe for healing of HSV-2 lesions

A

1-3 weeks

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14
Q

systemic s/s with HSV-2?

A

possibly

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15
Q

reactivation of HSV-2 associated with

A

prodrome

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16
Q

prodrome

A

tingling or pain

17
Q

varicella-zoster responsible for

A
  • chickenpox

- shingles

18
Q

varicella-zoster primary infection

19
Q

varicella-zoster secondary infection

20
Q

ratio of people who will develop shingles after having chickenpox

21
Q

Where does varicella-zoster often persist in the body?

A

dorsal root ganglia

22
Q

How is varicella-zoster acquired?

A

airborne droplets

23
Q

varicella-zoster activity

A
  • multiplies at site of entry

- spreads to bloodstream

24
Q

How long does varicella-zoster take to spread to bloodstream?

25
Incubation period for varicella-zoster
14-16 days from exposure
26
When does is varicella-zoster contagious?
- 1-2 days prior to demo of tx | - maintains contagiousness until lesions have crusted
27
How is shingles different from chickenpox?
eruptions follow dermatome distribution
28
PHN
post-herpetic neuralgia
29
PHN is associated with this, and may last a lifetime
shingles
30
What can happen with PHN?
- pain - hyperalgesia - allodynia
31
hyperalgesia
increased pain from a painful stimulus
32
allodynia
painful rxn to nonpainful stimulus
33
What is herpes-zoster ophthalmicus?
- medical emergency | - VZV near the eye that needs eval by ophthalmologist
34
What increases risk of shingles?
- over 50 | - immunocompromised
35
causes of shingles
- multifactorial | - related to cell-mediated immunity